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Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

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Annular Alopecia Areata: A Morphologically Rare Variant.

Shimona Garg¹, Anand Kumar¹, Mala Bhalla¹

¹Department of Dermatology and Venereology, Government Medical College and Hospital, Chandigarh, India.

International Journal of Trichology

|February 15, 2018

Summary

Alopecia areata, a common nonscarring hair loss condition, can present with unusual annular (ring-shaped) patterns. This report highlights two such rare cases, expanding the understanding of alopecia areata morphology.

Keywords:

Alopecia annular hair loss scalp

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Area of Science:

Dermatology
Trichology
Autoimmune diseases

Background:

Alopecia areata (AA) is a prevalent autoimmune condition causing nonscarring hair loss.
Typically presents as round or oval patches on the scalp or body.
Increasing recognition of diverse morphological variants beyond classic patterns.

Observation:

Two distinct cases of alopecia areata exhibiting an unusual annular (ring-shaped) hair loss pattern were observed.
The morphology deviated from the commonly described oval or round presentations.
Detailed clinical examination confirmed the annular configuration of hair loss.

Findings:

The annular pattern represents a rare but distinct morphological variant of alopecia areata.
This presentation challenges the typical understanding of AA lesion shapes.
Histopathological correlation, if performed, would further elucidate the nature of this variant.

Implications:

Broadens the differential diagnosis for annular hair loss.
Highlights the importance of recognizing unusual presentations of common dermatological conditions.
May prompt further research into the specific mechanisms or triggers of annular alopecia areata.