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Updated: Feb 14, 2026

Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
Management of traumatic brain injury patients
Hari Hara Dash1, Siddharth Chavali2
1Department of Anesthesiology and Pain Medicine, Fortis Memorial Research Institute, Gurgaon, India.
Insights
Severe traumatic brain injury (TBI) management has shifted towards protocol-based guidelines. This review details current approaches for preventing intracranial hypertension and secondary brain injury in TBI patients.
Area of Science:
- Neuroscience
- Trauma Surgery
- Critical Care Medicine
Background:
- Traumatic brain injury (TBI) is a major cause of death and disability globally in young individuals.
- Current TBI management emphasizes preventing secondary brain injury and optimizing cerebral oxygenation.
Purpose of the Study:
- To review protocol-based management strategies for severe TBI.
- To highlight recent guidelines for TBI care.
Main Methods:
- Review of current literature and guidelines on severe TBI management.
- Discussion of protocol-driven interventions.
Main Results:
- Protocol-based management is crucial for severe TBI.
- Key goals include controlling intracranial pressure and maintaining cerebral perfusion.
Conclusions:
- Adherence to protocol-based guidelines improves outcomes in severe TBI.
- Prompt management of intracranial hypertension and secondary brain injury is essential.
Abstract:
Traumatic brain injury (TBI) has been called the 'silent epidemic' of modern times, and is the leading cause of mortality and morbidity in children and young adults in both developed and developing nations worldwide. In recent years, the treatment of TBI has undergone a paradigm shift. The management of severe TBI is ideally based on protocol-based guidelines provided by the Brain Trauma Foundation. The aims and objectives of its management are prophylaxis and prompt management of intracranial hypertension and secondary brain injury, maintenance of cerebral perfusion pressure, and ensuring adequate oxygen delivery to injured brain tissue. In this review, the authors discuss protocol-based approaches to the management of severe TBI as per recent guidelines.
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