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Unlike ionic or small covalent molecules, polymers do not form crystalline solids due to the diffusion limitations of their long-chain structures. However, polymers contain microscopic crystalline domains separated by amorphous domains.
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Particles in a solid are tightly packed together (fixed shape) and often arranged in a regular pattern; in a liquid, they are close together with no regular arrangement (no fixed shape); in a gas, they are far apart with no regular arrangement (no fixed shape). Particles in a solid vibrate about fixed positions (cannot flow) and do not generally move in relation to one another; in a liquid, they move past each other (can flow) but remain in essentially constant contact; in a gas, they move...
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Microfluidic Preparation of Liquid Crystalline Elastomer Actuators
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Liquid-crystalline nanoarchitectures for tissue engineering.

Baeckkyoung Sung1,2, Min-Ho Kim2

  • 1Liquid Crystal Institute and Chemical Physics Interdisciplinary Program, Kent State University, Kent, OH 44242, USA.

Beilstein Journal of Nanotechnology
|February 15, 2018
PubMed
Summary
This summary is machine-generated.

Liquid crystals (LCs) mimic biological structures for advanced nanobiomaterials. This review explores LC nanoarchitectures for tissue engineering, focusing on regenerative potential and future applications.

Keywords:
biocolloidbiopolymercell-matrix interactionmesophaseregenerative medicine

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Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Nanotechnology

Background:

  • Biological systems exhibit hierarchical orders, with tissues and cells displaying liquid crystal (LC) properties.
  • There is growing interest in leveraging LC templates and scaffolds for engineering novel nanobiomaterials.

Purpose of the Study:

  • To review and correlate diverse LC nanoarchitectures with their biological functionalities.
  • To summarize tissue-mimicking LC materials and their regenerative potential for hard and soft tissues.
  • To envisage the application of LC architectures in developing tissue-engineered products.

Main Methods:

  • Review of existing literature on liquid crystal nanoarchitectures.
  • Correlation of LC properties with biological functionalities in tissue engineering.
  • Analysis of different LC phases and their impact on tissue regeneration.

Main Results:

  • Diverse LC nanoarchitectures can be engineered to mimic biological tissues.
  • LC materials exhibit potential for regenerating both hard and soft tissues.
  • Various LC phases offer multifaceted approaches for tissue engineering.

Conclusions:

  • LC nanoarchitectures hold significant promise for advancing tissue engineering.
  • Further research is needed to overcome challenges and fully exploit the opportunities in this field.