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Published on: March 20, 2018
Disability Weights for Pediatric Surgical Procedures: A Systematic Review and Analysis
Emily R Smith1,2, Tessa Concepcion3, Stephanie Lim4
1Robbins College of Health and Human Services, Baylor University, Waco, TX, USA. emily.smith1@duke.edu.
Insights
Disability weights (DWs) for pediatric surgical conditions are poorly defined, especially in low- and middle-income countries (LMICs). Existing DWs are inadequate for accurately measuring the burden of these conditions, necessitating the development of new metrics.
Area of Science:
- Global Health
- Pediatric Surgery
- Health Economics
Background:
- Disability weights (DWs) are crucial for measuring the burden of disease, but are poorly defined for pediatric surgical conditions.
- Accurate metrics are needed to assess the cost-effectiveness and impact of pediatric surgical interventions in low- and middle-income countries (LMICs).
Purpose of the Study:
- To systematically review existing disability weights (DWs) for pediatric surgical conditions in LMICs.
- To evaluate the adequacy of current DWs for quantifying the burden of pediatric surgical disease.
Main Methods:
- Systematic literature search of MEDLINE for pediatric surgery cost-effectiveness studies in LMICs (1996-2017).
- Inclusion of DWs from Global Burden of Disease studies, bibliographies, and expert opinion.
- Analysis of 194 discrete DWs for 66 pediatric surgical conditions.
Main Results:
- The Global Burden of Disease studies were the primary source of DWs (72%).
- Only a small fraction of reported DWs reflected pre- (12) or post-surgical (12) severity.
- Significant variation in methodological quality was observed among included studies and DWs.
Conclusions:
- Existing disability weights are insufficient for accurately quantifying the burden of pediatric surgical conditions.
- Development of a comprehensive set of DWs is needed, considering pediatric-specific factors and disease severity.
- Improved metrics are essential for informed policy decisions regarding pediatric surgical care in LMICs.
Background:
Metrics to measure the burden of surgical conditions, such as disability weights (DWs), are poorly defined, particularly for pediatric conditions. To summarize the literature on DWs of children's surgical conditions, we performed a systematic review of disability weights of pediatric surgical conditions in low- and middle-income countries (LMICs).
Method:
For this systematic review, we searched MEDLINE for pediatric surgery cost-effectiveness studies in LMICs, published between January 1, 1996, and April 1, 2017. We also included DWs found in the Global Burden of Disease studies, bibliographies of studies identified in PubMed, or through expert opinion of authors (ES and HR).
Results:
Out of 1427 publications, 199 were selected for full-text analysis, and 30 met all eligibility criteria. We identified 194 discrete DWs published for 66 different pediatric surgical conditions. The DWs were primarily derived from the Global Burden of Disease studies (72%). Of the 194 conditions with reported DWs, only 12 reflected pre-surgical severity, and 12 included postsurgical severity. The methodological quality of included studies and DWs for specific conditions varied greatly.
Interpretation:
It is essential to accurately measure the burden, cost-effectiveness, and impact of pediatric surgical disease in order to make informed policy decisions. Our results indicate that the existing DWs are inadequate to accurately quantify the burden of pediatric surgical conditions. A wider set of DWs for pediatric surgical conditions needs to be developed, taking into account factors specific to the range and severity of surgical conditions.
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