Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Buffer Effectiveness02:19

Buffer Effectiveness

55.6K
Buffer solutions do not have an unlimited capacity to keep the pH relatively constant . Instead, the ability of a buffer solution to resist changes in pH relies on the presence of appreciable amounts of its conjugate weak acid-base pair. When enough strong acid or base is added to substantially lower the concentration of either member of the buffer pair, the buffering action within the solution is compromised.
The buffer capacity is the amount of acid or base that can be added to a given volume...
55.6K
Framing Effects03:26

Framing Effects

8.0K
Information is everywhere and its presentation—such as how and when items are presented—can impact our perceptions and decisions surrounding the info. This broad concept umbrellas framing effects—influences that occur due to the way information is framed in its appearance, whether it’s purely the order or the specific wording of a message. Let’s take a look at numerous ways in which two versions of something can objectively say the same thing, yet we respond in...
8.0K
Biological Effects of Radiation02:59

Biological Effects of Radiation

18.1K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
18.1K
Sustainable Development01:43

Sustainable Development

15.2K
As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
15.2K
Self-Awareness and Its Effects01:21

Self-Awareness and Its Effects

318
Self-awareness is a psychological state in which the individual becomes the focal point of their attention. This inward focus transforms the self into an object of contemplation and assessment, influencing how individuals perceive their actions and their alignment with personal and societal standards.Triggers and Contexts for Self-AwarenessSelf-awareness can be activated by external stimuli that make individuals visually or audibly aware of themselves, such as mirrors, cameras, or recordings.
318
Effects of feedback01:24

Effects of feedback

1.1K
Feedback in control systems plays a critical role in shaping various operational parameters, extending beyond simple error reduction to influence stability, bandwidth, gain, impedance, and sensitivity. Understanding these effects requires examining a basic feedback system characterized by defined input, output, error, and feedback signals.
Feedback significantly modifies the gain of a control system. The gain of a system without feedback is altered by a factor of one plus GH, where G represents...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inhibition of acetylcholinesterase and histopathological changes in Aedes aegypti and Aedes albopictus larvae exposed to ethanolic extract of Acmella oleracea (L.) R.K. Jansen (Asteraceae).

Brazilian journal of biology = Revista brasleira de biologia·2025
Same author

Non-permeable cryoprotectants' influence on fibroblast slow freezing in six-banded armadillo.

Cryo letters·2025
Same author

Mechanical and Optical Characterization of Single-shade Resin Composites Used in Posterior Teeth.

Operative dentistry·2024
Same author

PERSPECTIVE: Potential and reality of cryopreserving somatic cells of wild felids for conservation.

Cryo letters·2023
Same author

Interactions among sucrose and concentrations of serum fetal bovine on the cryopreservation of somatic cells derived from red-rumped agoutis.

Cryo letters·2023
Same author

Effect of carvacrol antioxidant capacity on oocyte maturation and embryo production in cattle.

Zygote (Cambridge, England)·2023
Same journal

Comparative <i>In Vitro</i> Release Profiling of Brand and Generic Metoprolol Extended-Release Formulations in the Context of Product Switching.

Die Pharmazie·2026
Same journal

The Role of SGLT2 Inhibitors in the Management of Diabetic Retinopathy: A Literature Review.

Die Pharmazie·2026
Same journal

Research Progress on Ferroptosis-Inducing Compounds in Tumor Cells.

Die Pharmazie·2026
Same journal

Mocetinostat Ameliorates Pathological Cardiac Hypertrophy via Suppression of Ferroptosis Through Nrf2 Pathway.

Die Pharmazie·2026
Same journal

Different Effects of the Anticonvulsant Drugs Phenytoin and Phenobarbital on Forskolin-Induced BeWo Syncytialization.

Die Pharmazie·2026
Same journal

MC4R Antagonists: A Promising New Hope for the Treatment of Cachexia and Wasting Diseases.

Die Pharmazie·2026
See all related articles

Related Experiment Video

Updated: Feb 14, 2026

Metabolic Profiling to Determine Bactericidal or Bacteriostatic Effects of New Natural Products using Isothermal Microcalorimetry
07:28

Metabolic Profiling to Determine Bactericidal or Bacteriostatic Effects of New Natural Products using Isothermal Microcalorimetry

Published on: October 29, 2020

9.4K

PLGA Implants containing vancomycin and dexamethasone: development, characterization and bactericidal effects.

A F C Resende, A F Pereira, T P Moreira

    Die Pharmazie
    |February 15, 2018
    PubMed
    Summary
    This summary is machine-generated.

    New poly(lactic-co-glycolic acid) (PLGA) implants deliver vancomycin and dexamethasone to treat post-operative endophthalmitis, offering a potential alternative to eye injections.

    More Related Videos

    A High-throughput Shigella-specific Bactericidal Assay
    06:11

    A High-throughput Shigella-specific Bactericidal Assay

    Published on: February 27, 2019

    12.5K
    Protocol for Human Blastoids Modeling Blastocyst Development and Implantation
    12:09

    Protocol for Human Blastoids Modeling Blastocyst Development and Implantation

    Published on: August 10, 2022

    7.4K

    Related Experiment Videos

    Last Updated: Feb 14, 2026

    Metabolic Profiling to Determine Bactericidal or Bacteriostatic Effects of New Natural Products using Isothermal Microcalorimetry
    07:28

    Metabolic Profiling to Determine Bactericidal or Bacteriostatic Effects of New Natural Products using Isothermal Microcalorimetry

    Published on: October 29, 2020

    9.4K
    A High-throughput Shigella-specific Bactericidal Assay
    06:11

    A High-throughput Shigella-specific Bactericidal Assay

    Published on: February 27, 2019

    12.5K
    Protocol for Human Blastoids Modeling Blastocyst Development and Implantation
    12:09

    Protocol for Human Blastoids Modeling Blastocyst Development and Implantation

    Published on: August 10, 2022

    7.4K

    Area of Science:

    • Ophthalmology
    • Biomaterials Science
    • Infectious Diseases

    Background:

    • Post-operative endophthalmitis is a severe ocular infection following eye surgery.
    • Current treatment involves intraocular drug injections, which can cause complications.
    • Intraocular implants offer a potential alternative drug delivery system.

    Purpose of the Study:

    • To evaluate poly(lactic-co-glycolic acid) (PLGA) implants loaded with vancomycin and dexamethasone.
    • To assess their efficacy as a drug delivery system for treating endophthalmitis after cataract surgery.

    Main Methods:

    • Characterization of PLGA implants using FTIR, DSC, WAXS, and SEM.
    • Assessment of drug content uniformity and in vitro drug release kinetics.
    • Evaluation of the bactericidal effect of eluted vancomycin against Staphylococcus aureus and epidermidis.

    Main Results:

    • Drugs were uniformly distributed within the PLGA polymer matrix.
    • Analytical techniques confirmed the chemical integrity of incorporated drugs.
    • Controlled drug release was observed, with eluted vancomycin demonstrating bactericidal activity.
    • Dexamethasone's semi-crystalline nature was modified within the implant.

    Conclusions:

    • PLGA implants effectively deliver vancomycin and dexamethasone for controlled release.
    • These implants show promise as a therapeutic alternative for post-operative endophthalmitis.
    • This approach may reduce complications associated with conventional intraocular injections.