Related Experiment Video
Updated: Feb 14, 2026

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
Published on: September 28, 2015
Subcutaneous Infusion of Fluids for Hydration or Nutrition: A Review
Riccardo Caccialanza1, Thierry Constans2, Paolo Cotogni3
1Servizio di Dietetica e Nutrizione Clinica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Subcutaneous infusion effectively delivers hydration and nutrition with minimal complications, offering a safe alternative to intravenous methods. This technique is ideal for mild to moderate dehydration or when intravenous access is challenging.
Area of Science:
- Medical Science
- Clinical Practice
- Patient Care
Background:
- Subcutaneous infusion, also known as hypodermoclysis, involves fluid administration into the subcutaneous tissue.
- This technique is utilized for hydration and nutritional support, particularly when oral intake is insufficient.
Purpose of the Study:
- To review the technique of subcutaneous infusion.
- To summarize evidence on its use for hydration and nutrition.
- To describe indications, advantages, and disadvantages compared to intravenous infusion.
Main Methods:
- Literature review of studies on subcutaneous fluid infusion.
- Analysis of indications, effectiveness, safety, and complications.
- Comparison with intravenous infusion methods.
Main Results:
- Subcutaneous infusion is effective for hydration and nutrition with minimal complications.
- It demonstrates similar effectiveness and safety to the intravenous route.
- Advantages include ease of use, lower cost, and reduced risk of serious infections.
Conclusions:
- Subcutaneous infusion is a viable and safe option for fluid administration in specific patient populations.
- It is particularly suited for mild to moderate dehydration/malnutrition and difficult intravenous access.
- The technique is applicable across various healthcare settings, including home care.
Related Concept Videos
The Roles of Bacteria and Fungi in Plant Nutrition
Hydration of Cement
Aqueous Solutions and Heats of Hydration
When ionic compounds dissolve in water, the ions in the solid separate and disperse uniformly throughout the solution because water molecules surround and solvate the ions, reducing the strong electrostatic forces between them. This process...
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...

