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Updated: Feb 14, 2026

Primary Culture of Human Vestibular Schwannomas
Published on: July 20, 2014
A case report of rectal schwannoma treated with laparoscopic proctectomy
Kai Zhang1, Shanshan Qu, Junan Li
1Department of General Surgery Department of Pathology Department of Endoscopy, The Second Hospital of Jilin University, Changchun, Jilin. Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Rationale:
Schwannomas of gastrointestinal tracts are rare and difficult to detect preoperatively because of negative results of endoscopic and imaging examinations. Here, we reported a case of rectal schwannoma, which was diagnosed by immunohistochemical staining after laparoscopic protectomy.
Patient Concerns:
A 61-year-old woman complained of a 1-month history of difficulty in defecation and irregularly abdominal discomfort during her physical checkup in our hospital.
Diagnoses:
Immunohistochemical staining results after laparoscopic protectomy revealed a strong positive reaction for S-100 protein. Therefore, rectal schwannoma was confirmed.
Interventions:
Treatment with laparoscopic protectomy was given.
Outcomes:
Symptoms resolved completely after 12 days of the surgery, and was regular followed-up in outpatient clinic.
Lessons:
Schwannomas are difficult to identify preoperatively, and immunohistochemical staining for S-100 protein is an effective method to diagnose it.
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