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Fluorescence-activated Cell Sorting for Purification of Plasmacytoid Dendritic Cells from the Mouse Bone Marrow
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Plasmacytoid pre-dendritic cells (pDC): from molecular pathways to function and disease association

Solana Alculumbre1, Salvatore Raieli1, Caroline Hoffmann1

  • 1Institut Curie, PSL Research University, Institut National de la Santé et de la Recherche Médicale (INSERM), U932, F-75005 Paris, France.

Seminars in Cell & Developmental Biology
|February 15, 2018
PubMed
Summary

Plasmacytoid pre-dendritic cells (pDC) are key immune cells producing type I interferon (IFN) and initiating antiviral responses. Their functions impact disease outcomes in infection, autoimmunity, allergy, and cancer.

Keywords:
Adaptive immunityHuman diseasesInnate sensingPlasmacytoid dendritic cellsType I Interferon

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