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Updated: Feb 14, 2026

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
Published on: November 11, 2016
Primary growth hormone insensitivity and psychomotor delay
Inma Castilla-Cortazar1,2, Julieta Rodríguez De Ita1, Gabriel A Aguirre1
1Escuela de Medicina Tecnologico de Monterrey Monterrey Mexico.
Abstract:
We report a case of short stature irresponsive to growth hormone (GH) replacement therapy. Low GH response to provocative tests and undetectable IGF-1 levels had suggested GH deficiency, while response to therapy indicated GH insensitivity. Molecular evaluation of the GH/IGF-1 axis should be performed in these cases to improve diagnosis and therapy.
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