Related Experiment Video
Updated: Feb 14, 2026
Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice
Published on: April 14, 2011
Acute disseminated encephalomyelitis following Influenza A pneumonia
Babikir Kheiri1, Emad Abu Sitta1, Anas Salih1
1Internal Medicine Department Hurley Medical Center/Michigan State University Two Hurley Plaza, Ste 212 Flint Michigan 48503.
Abstract:
Acute disseminated encephalomyelitis (ADEM) is an autoimmune demyelinating disorder of the central nervous system and can present following influenza A infections as multifocal neurological deficits. ADEM remains a challenging diagnosis, and high clinical suspicious coupled with laboratory investigations and neuroimaging is required to exclude other primary and secondary demyelinating disorders.
Insights
Acute disseminated encephalomyelitis (ADEM) is an autoimmune disorder causing neurological deficits after influenza A. Diagnosing ADEM requires high clinical suspicion and excluding other demyelinating conditions.
Area of Science:
- Neuroimmunology
- Infectious Neurology
Background:
- Acute disseminated encephalomyelitis (ADEM) is a rare autoimmune demyelinating disease of the central nervous system.
- ADEM can manifest with multifocal neurological deficits, often following infections like influenza A.
Purpose of the Study:
- To highlight the diagnostic challenges of ADEM.
- To emphasize the importance of clinical suspicion in ADEM diagnosis.
Main Methods:
- Review of clinical presentations of ADEM.
- Discussion of diagnostic criteria for ADEM.
- Comparison with other demyelinating disorders.
Main Results:
- ADEM presents as multifocal neurological deficits.
- Influenza A is a potential trigger for ADEM.
- Differential diagnosis is crucial for accurate ADEM identification.
Conclusions:
- ADEM diagnosis necessitates a high index of clinical suspicion.
- Laboratory investigations and neuroimaging are essential to differentiate ADEM from other demyelinating disorders.
More Related Videos
09:17A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii
Published on: January 2, 2017
11:32Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Related Concept Videos
01:30Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
01:29Pneumonia II: Pathophysiology
01:28Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
01:30Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
01:30Pneumonia III: Complications and Assessment
01:30Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause: