Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Accelerators01:17

Accelerators

294
Accelerators in concrete serve as admixtures to speed up the hardening process, enabling the concrete to achieve early strength faster. Although accelerators do not necessarily impact the time it takes concrete to set, they reduce this time in practice. A common accelerator is calcium chloride, which is particularly useful for hastening early strength development in cold weather or for rapid repair jobs that require quick heat generation after mixing.
The effectiveness of calcium chloride can...
294
Parallel Processing01:20

Parallel Processing

780
The brain processes sensory information rapidly due to parallel processing, which involves sending data across multiple neural pathways at the same time. This method allows the brain to manage various sensory qualities, such as shapes, colors, movements, and locations, all concurrently. For instance, when observing a forest landscape, the brain simultaneously processes the movement of leaves, the shapes of trees, the depth between them, and the various shades of green. This enables a quick and...
780
Parallel Resonance01:23

Parallel Resonance

609
The parallel RLC circuit is an arrangement where the resistor (R), inductor (L), and capacitor (C) are all connected to the same nodes and, as a result, share the same voltage across them. The parallel RLC circuit is analyzed in terms of admittance (Y), which reflects the ease with which current can flow. The admittance is given by:
609
Resistors In Parallel01:23

Resistors In Parallel

6.4K
Resistors are in parallel when one end of all the resistors are connected to a continuous wire of negligible resistance and the other end of all the resistors are also connected to one another through a continuous wire of negligible resistance. In the case of a parallel configuration, the potential drop across each resistor is the same. Current through each resistor can be found using Ohm’s law, I = V/R, where the voltage is constant across each resistor. The sum of the individual currents...
6.4K
Average Acceleration01:30

Average Acceleration

14.6K
The importance of understanding acceleration spans our day-to-day experiences, as well as the vast reaches of outer space and the tiny world of subatomic physics. In everyday conversation, to accelerate means to speed up. For instance, we are familiar with the acceleration of our car; the harder we apply our foot to the gas pedal, the faster we accelerate. The greater the acceleration, the greater the change in velocity over a given time. Acceleration is widely seen in experimental physics. In...
14.6K
Instantaneous Acceleration01:16

Instantaneous Acceleration

23.4K
Acceleration is in the direction of the change in velocity, but it is not always in the direction of motion. When an object slows down, its acceleration is opposite to the direction of its motion. Although commonly referred to as deceleration, this causes confusion in our analysis as deceleration is not a vector, and does not point to a specific direction with respect to a coordinate system. Therefore, the term deceleration is not used. For example, when a subway train slows down, it...
23.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Normative T<sub>1</sub> and T<sub>2</sub> Brain Atlases Across the Adult Lifespan in a Chinese Cohort: Multicenter Quantitative MRI Benchmarks for Ageing and Neurodegenerative Research.

Human brain mapping·2026
Same author

Introducing a translationally relevant mouse model of radiosurgery-induced unilateral hearing loss.

Frontiers in neuroscience·2026
Same author

Healthy knee cartilage T2 mapping assessed with GRAPPATINI and multi-echo spin-echo (MESE) at 3T: regional values, longitudinal repeatability and method agreement.

Quantitative imaging in medicine and surgery·2026
Same author

Reducing Noise Induced by Cardiac Pulsatility in Brain Maps of R<sub>2</sub>* and Magnetic Susceptibility Using Tailored k-space Sampling.

NMR in biomedicine·2026
Same author

How Much Does Motion Matter? Evaluating the Motion Robustness of pTx Pulses at 7 T.

Magnetic resonance in medicine·2026
Same author

Improved image quality and reduced acquisition time in brain MRI using deep learning-based reconstruction: A quantitative and subjective assessment compared to standard MPRAGE in 0.55 T MRI.

Magnetic resonance imaging·2026
Same journal

Editorial for "Association Between Deep Gray Matter Iron Deposition Dysregulation and Cognitive Performance in Type 2 Diabetes Mellitus Patients: A Quantitative Susceptibility Mapping Study".

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Association Between Deep Gray Matter Iron Deposition Dysregulation and Cognitive Performance in Type 2 Diabetes Mellitus Patients: A Quantitative Susceptibility Mapping Study.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Association of Iron and Myelin Alterations in the Contralesional Dentate Nucleus and Thalamus With Functional Outcome in Acute Ischemic Stroke: A Susceptibility Source Separation Study.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

A Quantitative Modification of VI-RADS for Bladder Cancer at the Ureteral Orifice: A Reader Study on MRI With Varying Experience Levels.

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Editorial for "Integrating nnU-Net Segmentation and Clinical-Radiomics for Multicenter Prediction of Soft Tissue Sarcoma Grade and Ki-67 Expression".

Journal of magnetic resonance imaging : JMRI·2026
Same journal

Structural MRI Volumetry Index for Differentiation of Progressive Supranuclear Palsy From Parkinson's Disease and Multiple System Atrophy by Automatic Segmentation: A Comparison With Magnetic Resonance Parkinsonism Index.

Journal of magnetic resonance imaging : JMRI·2026
See all related articles

Related Experiment Video

Updated: Feb 14, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.3K

Accelerated T2 mapping combining parallel MRI and model-based reconstruction: GRAPPATINI.

Tom Hilbert1,2,3, Tilman J Sumpf4, Elisabeth Weiland5

  • 1Advanced Clinical Imaging Technology (HC CEMEA SUI DI PI), Siemens Healthcare, Lausanne, Switzerland.

Journal of Magnetic Resonance Imaging : JMRI
|February 16, 2018
PubMed
Summary
This summary is machine-generated.

Accelerated quantitative T2 mapping using GRAPPATINI provides fast, reproducible whole-brain T2 maps and synthetic T2-weighted images in under two minutes. This technique enhances clinical applications for disease biomarker detection.

Keywords:
T2 mappingmodel-based reconstructionparametric mappingquantitative MRI

More Related Videos

Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging MRI
06:30

Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging MRI

Published on: December 16, 2021

4.5K
MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges
09:33

MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges

Published on: December 17, 2014

14.6K

Related Experiment Videos

Last Updated: Feb 14, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.3K
Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging MRI
06:30

Endovascular Perforation Model for Subarachnoid Hemorrhage Combined with Magnetic Resonance Imaging MRI

Published on: December 16, 2021

4.5K
MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges
09:33

MRI Mapping of Cerebrovascular Reactivity via Gas Inhalation Challenges

Published on: December 17, 2014

14.6K

Area of Science:

  • Magnetic Resonance Imaging
  • Biomedical Engineering
  • Quantitative Imaging

Background:

  • Quantitative T2 measurements are valuable biomarkers for detecting water accumulation and myelin loss.
  • However, traditional T2 measurement techniques require lengthy acquisition times, limiting clinical utility.

Purpose of the Study:

  • To accelerate T2 quantification and synthetic T2-weighted (T2-w) image generation for clinical research and routine use.
  • To enable high-resolution T2 mapping and T2-w images of the entire brain in under two minutes.

Main Methods:

  • Extended the model-based approach for rapid T2 and M0 quantification (MARTINI) with parallel imaging (GRAPPA).
  • Assessed accuracy and reproducibility using phantom and in-vivo MRI studies (brain, knee, prostate, liver).
  • Generated synthetic T2-w images from computed T2 and M0 maps and compared them to conventional fast spin-echo (SE) images.

Main Results:

  • The combined GRAPPA and MARTINI (GRAPPATINI) achieved 10-fold acceleration, enabling whole-brain T2 mapping in 1:44 minutes.
  • GRAPPATINI demonstrated significantly lower root mean square distance (4.3%) compared to MARTINI alone (37.6%) against the reference.
  • Excellent reproducibility was observed with low standard deviations in T2 values across scans and subjects.

Conclusions:

  • GRAPPATINI enables highly reproducible, rapid whole-brain T2 mapping and synthetic T2-w image generation within clinically feasible acquisition times.
  • This accelerated quantitative T2 mapping technique is poised to broaden its clinical applications for disease assessment.