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Contrast Enhanced Vessel Imaging using MicroCT
Published on: January 27, 2011
Three-Dimensional Radial VIBE Sequence for Contrast-Enhanced Brain Imaging: An Alternative for Reducing Motion
Ji Eun Park1,2, Young Hun Choi1,3, Jung-Eun Cheon1,3,4
11 Department of Radiology, Seoul National University Children's Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080 Korea.
Objective:
The purpose of this study was to evaluate the usefulness of radially sampled 3D fat-suppressed T1-weighted gradient-echo sequences (radial volumetric interpolated breath-hold examination [radial VIBE]) for contrast-enhanced brain MRI of children through comparison with a magnetization-prepared rapid-acquisition gradient-echo (MP-RAGE) sequence.
Materials And Methods:
Sixty-five consecutive contrast-enhanced brain MRI examinations performed with axial MP-RAGE and radial VIBE sequences were included. For quantitative analysis, coefficients of variation of gray matter and white matter and CSF and relative contrast between tissue types (gray matter and white matter, gray matter and CSF, and white matter and CSF) for each sequence were calculated. For qualitative assessment, motion, pulsation artifacts, overall image quality, and lesion conspicuity were retrospectively scored on a 5-point scale. Quantitative and qualitative subgroup analyses were performed for patients with serious motion artifacts.
Results:
Images obtained with the radial VIBE sequence had fewer motion and pulsation artifacts than those obtained with the MP-RAGE sequence (MP-RAGE vs radial VIBE motion score, 3.57 ± 1.00 vs 4.52 ± 0.51; pulsation score, 3.57 ± 0.60 vs 4.91 ± 0.21; all p < 0.001). Among 25 images with serious motion artifacts, radial VIBE images had significantly higher scores for all qualitative parameters, including overall image quality, than did MP-RAGE images (overall image quality for MP-RAGE vs radial VIBE, 2.63 ± 0.82 vs 3.42 ± 0.55, p < 0.001).
Conclusion:
The study showed that a radial fat-suppressed T1-weighted gradient-echo sequence is a viable alternative to conventional cartesian acquisition for contrast-enhanced brain imaging of restless children.
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