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Recent Advances in Antioxidant Cosmeceutical Topical Delivery
Shymaa Hatem1, Maha Nasr2,3, Seham A Elkheshen1
1Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences and Pharmaceutical Industries, Future University in Egypt, New Cairo, Egypt.
Current Drug Delivery
|February 16, 2018
Summary
Delivery carriers enhance topical antioxidant efficacy for skin aging and protection. This review covers vesicular, lipidic, polymeric, and carbon nanotube systems for improved antioxidant skin delivery.
Area of Science:
- Cosmeceuticals and dermatology
- Materials science in drug delivery
Background:
- Antioxidants are crucial cosmeceuticals for inhibiting cellular damage and minimizing skin aging.
- Topical antioxidant application protects skin from free radicals but faces challenges like chemical instability and poor skin penetration.
- Unfavorable physicochemical properties hinder antioxidant effectiveness and delivery to deeper skin layers.
Purpose of the Study:
- To review various delivery carriers for enhancing topical antioxidant effects against skin aging.
- To discuss the application of different carrier systems in improving antioxidant delivery to the skin.
Main Methods:
- Review of scientific literature on delivery systems for topical antioxidants.
- Analysis of vesicular, lipidic, polymeric, and carbon nanotube systems.
- Evaluation of carrier systems' success in improving antioxidant benefits for skin.
Main Results:
- Delivery carriers effectively overcome physicochemical barriers of antioxidants.
- Vesicular, lipidic, polymeric systems, and carbon nanotubes show significant improvements in antioxidant delivery.
- These systems enhance antioxidant efficacy against skin aging and cellular damage.
Conclusions:
- Delivery carriers are essential for optimizing topical antioxidant performance.
- Advanced carrier systems like nanoparticles and liposomes are key to effective antioxidant skin treatments.
- Utilizing these carriers maximizes the anti-aging and protective benefits of antioxidants.
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