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Flame figures in linear IgA bullous dermatosis: a novel histopathologic finding
E Fulton1, F Jan, M J Zimarowski
1Beth Israel Deaconess Medical Center, Department of Pathology, Harvard Medical School, Boston, Massachusetts.
This case report describes Linear IgA bullous dermatosis (LABD) with unusual eosinophilic inflammation and flame figures. These findings highlight the importance of comprehensive diagnostic methods for bullous dermatoses.
Area of Science:
- Dermatology
- Immunodermatology
- Histopathology
Background:
- Linear IgA bullous dermatosis (LABD) is an autoimmune blistering disease characterized by IgA deposition at the basement membrane zone (BMZ) and neutrophil-rich inflammation.
- Typical histopathology of LABD involves neutrophils, but this case presents with numerous eosinophils and flame figures, a previously unreported finding.
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