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Infectious Scarring: Setting the Trigger for Intestinal Inflammation
Andrew M F Johnson1, R William DePaolo1
1Division of Gastroenterology, Department of Medicine, University of Washington, Seattle, WA, USA.
Abstract:
The initiating factors that trigger inflammatory bowel disease (IBD) are poorly understood. In a recent paper, Yang et al. (2017) demonstrate that IBD-like syndrome in mice can develop as a consequence of recurrent pathogen infection. Pathogenic triggering of inflammatory disease is a re-emerging concept that has significant therapeutic implications.
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