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Related Experiment Videos

Pediatric Meniere's disease.

Chi Wang1, Chien-Hao Wu2, Po-Wen Cheng2

  • 1Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan.

International Journal of Pediatric Otorhinolaryngology
|February 16, 2018
PubMed
Summary
This summary is machine-generated.

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Pediatric Meniere

Area of Science:

  • Otolaryngology
  • Pediatric Neurology
  • Vestibular System Disorders

Background:

  • Meniere's disease (MD) is a rare inner ear disorder.
  • Pediatric MD accounts for only 2.3% of all MD cases.
  • Understanding the progression of inner ear deficits in children is crucial.

Purpose of the Study:

  • To investigate the sequence of inner ear deficits in pediatric Meniere's disease.
  • To utilize a comprehensive inner ear test battery including audiometry, oVEMP, cVEMP, and caloric tests.
  • To compare the deficit sequence in children with that observed in adults.

Main Methods:

  • A cohort of 24 children (<15 years) with MD was studied between 2005 and 2016.
  • Included otoscopy, CT scan, blood tests, and an inner ear test battery.
Keywords:
Cervical vestibular evoked myogenic potential (cVEMP)ChildrenMeniere's diseaseOcular vestibular evoked myogenic potential (oVEMP)Vestibular migraine

Related Experiment Videos

  • Assessed hearing, cochlear (cVEMP), saccular (oVEMP), and semicircular canal (caloric) function.

    • Main Results:

    • Inner ear deficits progressed from cochlear (hearing loss) to saccular (cVEMP), then utricular (oVEMP), and finally semicircular canals (caloric tests).
    • Abnormalities were observed in 25% for hearing, 20% for cVEMP, 13% for oVEMP, and 12% for caloric tests.
    • A positive correlation was found between family history and laterality of the disease.

    Conclusions:

    • Pediatric Meniere's disease exhibits a distinct sequence of inner ear dysfunction, mirroring adult patterns.
    • The observed sequence involves cochlear, saccular, utricular, and semicircular canal deficits.
    • A positive family history in one-third of cases may contribute to bilateral and symmetrical Meniere's disease in children.