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Estrogenicity of Octyl Glucoside Synthesized by Direct Glucosidation as Non-Endocrine Disruptive Surfactant
Kyong-Hwan Chung1, Hangun Kim2, Young-Kwon Park3
1Department of Environmental Engineering, Sunchon National University, Suncheon 57922, Korea.
Abstract:
The estrogenicity of octyl glucoside was studied with its preparation method using microporous zeolites. Its estrogenicity was estimated using E-assay method to confirm the possibility as non-endocrine disruptive surfactant. The octyl glucoside was synthesized from D-glucose with 1-octanol by direct glucosidation. The high conversion of D-glucose was obtained on H-FAU zeolite which has a mild acid strength. The conversion and yield were improved with increasing of acid site amount of the zeolite catalysts. The octyl glucopyranoside is more hydrophilic than nonylphenol and has a high wettability. The octyl glucosides represented extremely lower estrogenic cell proliferation compared with nonylphenol.
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