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Corneal hysteresis and primary open angle glaucoma.

Dascalescu Dana1, Constantin Mihaela2, Iancu Raluca3

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Corneal hysteresis (CH) is linked to visual field index (VFI) in primary open angle glaucoma (POAG) patients and healthy individuals. Lower CH correlates with poorer VFI, suggesting Ocular Response Analyzer utility in POAG evaluation.

Keywords:
corneaglaucomahysteresis

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Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Corneal Biomechanics

Background:

  • Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness.
  • Corneal hysteresis (CH) reflects biomechanical properties of the cornea.
  • Variability in CH may impact glaucoma assessment.

Purpose of the Study:

  • To examine the relationship between corneal hysteresis (CH) and visual field index (VFI) in POAG patients.
  • To assess the utility of the Ocular Response Analyzer (ORA) in POAG evaluation.

Main Methods:

  • Investigated 99 eyes from POAG patients and a control group.
  • Measured intraocular pressure (IOP), CH, corneal resistance factor (CRF), central corneal thickness (CCT), and visual field parameters (MD, PSD, VFI).
  • Utilized Goldman Aplanotonometer, Ocular Response Analyzer (ORA), ultrasonic pachymetry, and Humphrey visual field testing.

Main Results:

  • A significant positive correlation between CH and VFI was observed in both POAG patients (r=0.52, P<0.0001) and controls (r=0.22, p<0.04).
  • Lower CH was associated with a lower VFI in both study groups.

Conclusions:

  • Corneal hysteresis is significantly correlated with visual field index in both glaucoma and control groups.
  • The Ocular Response Analyzer (ORA) is a valuable tool for assessing POAG patients.
  • Findings suggest CH may serve as an indicator of visual field status in glaucoma.