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Related Experiment Video

Updated: Feb 14, 2026

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

Reengineering deep brain stimulation for movement disorders: Emerging technologies.

Aysegul Gunduz^1,2, Kelly D Foote^2,3, Michael S Okun^2,4

¹J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA.

Current Opinion in Biomedical Engineering

|February 17, 2018

Summary

Deep brain stimulation (DBS) offers a promising treatment for movement disorders. Engineering innovations in DBS technology, including novel patterns and closed-loop systems, aim to enhance clinical outcomes and accessibility.

Keywords:

DBS Deep brain stimulation Movement disorders Neuromodulation Neurostimulator

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Last Updated: Feb 14, 2026

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Deep Brain Stimulation with Simultaneous fMRI in Rodents

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Published on: February 15, 2014

Area of Science:

Neurosurgery
Biomedical Engineering

Background:

Deep brain stimulation (DBS) is a key therapy for drug-resistant movement disorders.
Successful DBS relies on surgical precision, device technology, and expert programming.
Current programming requires extensive clinician time and patient visits.

Purpose of the Study:

To review engineering advancements enhancing DBS clinical implementation.
To explore innovations improving DBS therapeutic benefits and accessibility.

Main Methods:

Review of novel temporal stimulation patterns.
Analysis of innovative electrode designs for DBS.
Exploration of computational modeling for stimulation guidance.
Investigation of closed-loop DBS systems.
Assessment of remote programming technologies.

Main Results:

Engineering approaches can optimize DBS parameter settings.
Novel temporal patterns and electrode designs offer improved efficacy.
Computational models and closed-loop systems promise personalized stimulation.
Remote programming can increase accessibility and efficiency.

Conclusions:

Engineering innovations are crucial for advancing DBS therapy.
Optimized DBS technologies can improve patient outcomes and broaden treatment reach.
Future DBS development should focus on intelligent and adaptive systems.