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Retrospective study of 152 feline cytological bone marrow examinations: preliminary classification and ranges

Vanessa Turinelli1, Alessandra Gavazza2

  • 11 IDEXX Laboratories-Italia, Milan, Italy.

Journal of Feline Medicine and Surgery
|February 17, 2018
PubMed

Insights

Feline bone marrow analysis revealed hyperplasia as the most common finding, followed by dysmyelopoiesis and malignant blood disorders. This study details the prevalence and cell counts for various feline bone marrow conditions.

Area of Science:

  • Veterinary Hematology
  • Comparative Pathology

Background:

  • Bone marrow cytology is crucial for diagnosing feline hematological disorders.
  • It is often the sole method for definitive diagnosis.

Purpose of the Study:

  • To determine the prevalence of feline bone marrow disorders in a European private laboratory.
  • To classify these disorders and analyze associated differential cell counts.

Main Methods:

  • 152 feline bone marrow samples were analyzed cytologically and numerically.
  • Samples were examined following identification of hematological alterations.

Main Results:

  • Hyperplasia was the most frequent finding (46.7%), predominantly granulocytic and erythroid.
  • Dysmyelopoiesis (15.1%) and malignant blood disorders (11.2%) were also significant.
  • Normal bone marrow was found in 13.8% of cases; hypoplasia in 9.9%.

Conclusions:

  • This study offers a prevalence overview of feline bone marrow disorders.
  • It provides reference ranges for differential cell counts and myeloid-to-erythroid ratios for various conditions.
Abstract

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