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Transitions in physiological coupling between heartbeat and pulse across sleep stages
Qianli D Y Ma1,2, Changjuan Ji2, Huanhuan Xie2
1College of Geographic and Biologic Information, Nanjing University of Posts and Telecommunications, Nanjing 210003, People's Republic of China.
Physiological Measurement
|February 17, 2018
Summary
The coupling strength between heartbeat and pulse decreases during sleep stages, offering a new method for automatic sleep staging using detrended cross-correlation analysis (DCCA) scaling exponents.
Area of Science:
- Cardiovascular Physiology
- Sleep Science
- Biomedical Signal Processing
Background:
- Heartbeat and pulse dynamics are complex and influenced by physiological states.
- Understanding cardiovascular regulation during sleep is crucial for health.
- Current sleep staging methods can be resource-intensive.
Purpose of the Study:
- To investigate the coupling between heartbeat and blood flow pulse across different sleep stages.
- To evaluate the feasibility of using this coupling strength for automatic sleep staging.
Main Methods:
- Recorded electrocardiogram (ECG) and photoplethysmography (PPG) signals during sleep.
- Extracted R-wave-to-R-wave intervals (RRI) and pulse-to-pulse intervals (PPI).
- Applied detrended cross-correlation analysis (DCCA) to quantify coupling strength and compared with detrended fluctuation analysis (DFA).
Main Results:
- DCCA scaling exponents between RRIs and PPIs decreased monotonically from wakefulness to deep sleep.
- This indicates a gradual reduction in heartbeat-pulse coupling strength upon entering deeper sleep stages.
- DCCA scaling exponents showed superior discrimination ability between wake/REM and light/deep sleep compared to DFA.
Conclusions:
- Heartbeat-pulse coupling strength exhibits regular changes across sleep stages, offering insights into cardiovascular regulation.
- DCCA scaling exponents serve as a reliable indicator for vigilance levels and automatic sleep staging.
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