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Serum creatinine concentration in children: normal values for sex and age

Insights

This study establishes normal serum creatinine reference ranges for individuals aged one day to 20 years. These findings provide crucial benchmarks for pediatric and adolescent kidney function assessment.

Area of Science:

  • Clinical Biochemistry
  • Pediatric Nephrology

Background:

  • Serum creatinine is a key indicator of kidney function.
  • Establishing age-specific reference ranges is essential for accurate diagnosis in pediatric populations.

Purpose of the Study:

  • To determine normal serum creatinine values in young individuals aged 1 year to 20 years.
  • To present preliminary serum creatinine data for male and female infants aged 1 day to 14 days.

Main Methods:

  • Analysis of serum creatinine levels in a cohort of 639 males and 631 females aged 1-20 years.
  • Collection of preliminary serum creatinine data from male and female infants (1 day-14 days).

Main Results:

  • Normal serum creatinine ranges were established for pediatric and adolescent populations.
  • Preliminary data indicate specific serum creatinine values for neonates and young infants.

Conclusions:

  • The study provides essential reference ranges for serum creatinine in children and adolescents.
  • These data support the accurate assessment of kidney function in young individuals, from infancy through adolescence.

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