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Updated: Feb 14, 2026

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Does reduced mastication influence cognitive and systemic health during aging?

Sophie Miquel1, Marcelo Aspiras1, Jon E L Day2

  • 1Mars Wrigley Confectionery, 1132 West Blackhawk Street, Chicago, IL 60642, USA.

Physiology & Behavior
|February 17, 2018
PubMed
Summary

Good oral health and chewing ability are linked to better cognitive and systemic health in older adults. Maintaining these factors may help reduce risks associated with aging.

Keywords:
AgingCognitive healthMasticationNeurogenesisSystemic health

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Area of Science:

  • Gerontology
  • Oral Health
  • Cognitive Science

Background:

  • Growing evidence links oral health and mastication to cognitive and systemic health in aging.
  • The direct versus independent deterioration of these factors with age remains unclear.

Purpose of the Study:

  • To review how reduced mastication influences cognitive and systemic health during aging.
  • To inform potential interventions for improving quality of life in older adults.

Main Methods:

  • Literature review of existing studies on mastication, oral health, cognitive function, and systemic health in aging populations.

Main Results:

  • Reduced mastication and oral health can directly impact systemic health via microbiota migration and indirectly through altered nutrient intake.
  • Tooth loss and decreased masticatory efficiency affect cognitive performance and health through mechanisms like neurogenesis and nutrient changes.

Conclusions:

  • Oral health and masticatory efficiency are modifiable factors influencing cognitive and systemic health risks in aging.
  • While promising, it is premature to recommend specific chewing interventions for cognitive decline.
  • Future research requires large-scale longitudinal studies controlling for confounding factors.