Necrotizing infection of the heart
David H Ballard1, George Patton Pennington2, George P Pennington3
1Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, United States.
Insights
Necrotizing infection of the heart, a rare condition, was identified in a 70-year-old woman presenting with chest and abdominal pain. Despite extensive investigation, the cause remained elusive until surgery revealed myocardial necrosis due to E. coli infection.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- Necrotizing infections typically affect soft tissues, with cardiac involvement being exceedingly rare.
- Early diagnosis of cardiac necrotizing infections is challenging due to vague presenting symptoms.
Observation:
- A 70-year-old female presented with non-specific chest and abdominal pain.
- Initial CT scans revealed gas within the myocardium of the left ventricle.
- Despite comprehensive imaging and exploratory surgery, no source of visceral perforation or diaphragmatic injury was identified.
Findings:
- Median sternotomy revealed necrotic tissue in the inferior wall of the heart.
- Cultures from the excised cardiac tissue identified Escherichia coli (E. coli) as the causative agent.
- The patient's condition rapidly deteriorated, leading to expiration post-operatively.
Implications:
- This case highlights the possibility of necrotizing cardiac infections, even in the absence of typical risk factors.
- Prompt recognition and surgical intervention are critical, though outcomes remain poor.
- Further research is needed to understand the pathogenesis and improve treatment strategies for this rare and fatal condition.
Abstract:
A case of necrotizing infection of the heart is presented. A 70-year-old woman presented with vague chest and abdominal pain. CT of the abdomen and pelvis was initially obtained, which demonstrated gas in the myocardium of the left ventricle. Subsequent chest CT, endoscopy, and abdominal surgical exploration did not reveal perforated viscus or diaphragm compromise. At median sternotomy, the inferior wall of the heart was found to be necrotic. Culture of the excised tissue grew E. coli. The patient expired shortly after surgical exploration.
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