Related Experiment Video
Updated: Feb 14, 2026

Normothermic Machine Perfusion of Rat Kidneys for Transplantation
Published on: January 27, 2026
Microsurgical anastomosis of renal vasculature in rats: A practical platform for acellular kidney transplantation
Abdol-Mohammad Kajbafzadeh1, Reza Khorramirouz1, Seyede Maryam Kameli1
1Pediatric Urology and Regenerative Medicine Research Center, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Abstract:
End-stage renal disease is becoming a contemporary global concern with increasing prevalence. The available treatment strategies are limited to dialysis and renal transplantation. However, limited organ supply and autoimmune rejection are the shortcomings that limit widespread application of transplantation. Favorably, regenerative medicine is able to provide acellular natural scaffolds for renal transplantation. Experimental surgeries in animal models are a fundamental step in transplantation research. This video presents a practical method for transplantation of bilateral acellular kidneys in a rat model, which could serve as a key step for further research.
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