Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Update on visual function and choroidal-retinal thickness alterations in Parkinson's disease.

J Obis1, M Satue1, R Alarcia1

  • 1Departamento de Oftalmología, Hospital Universitario Miguel Servet, Zaragoza, España.

Archivos De La Sociedad Espanola De Oftalmologia
|February 19, 2018
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genetic and serum biomarkers of NSAID hypersensitivity reactions.

Frontiers in pharmacology·2025
Same author

Progressive visual dysfunction and retinal neurodegeneration in patients with fibromyalgia.

Archivos de la Sociedad Espanola de Oftalmologia·2025
Same author

Update on the usefulness of optical coherence tomography-mediated angiography in neurodegenerative diseases.

Archivos de la Sociedad Espanola de Oftalmologia·2025
Same author

Orbital trochleitis: Literature review.

Archivos de la Sociedad Espanola de Oftalmologia·2024
Same author

Diagnosis of multiple sclerosis using optical coherence tomography supported by explainable artificial intelligence.

Eye (London, England)·2024
Same author

Influence of sex on chronic steroid-induced glaucoma: 24-Weeks follow-up study in rats.

Experimental eye research·2023

Optical coherence tomography (OCT) reveals retinal and choroidal changes in Parkinson's disease (PD). These OCT measurements may serve as a biomarker for PD progression and highlight early visual dysfunctions.

Area of Science:

  • Ophthalmology
  • Neurology
  • Biomedical Imaging

Background:

  • Parkinson's disease (PD) is a global neurodegenerative disorder affecting millions.
  • Optical coherence tomography (OCT) studies since 2004 have indicated retinal layer alterations in PD patients.
  • Discrepancies exist in OCT findings regarding PD, necessitating a comprehensive review.

Purpose of the Study:

  • To review existing literature on OCT and PD.
  • To identify specific retinal and choroidal parameters altered in PD.
  • To assess the clinical utility of OCT biomarkers and understand the impact of visual dysfunctions in PD.

Main Methods:

  • Systematic literature review of studies utilizing OCT in Parkinson's disease.
  • Analysis of OCT parameters including retinal thickness and choroidal thickness.
Keywords:
Choroidal thicknessEnfermedad de ParkinsonEspesor coroideoEspesor de la capa de fibras nerviosas de la retinaEspesor retinianoFunción visualOptical coherence tomographyParkinson's diseaseRetinal nerve fibre layer thicknessRetinal thicknessTomografía de coherencia ópticaVisual function

Related Experiment Videos

  • Correlation of OCT findings with PD severity, duration, and visual dysfunction.

    • Main Results:

    • OCT measurements show potential as non-invasive biomarkers for PD progression.
    • Some studies correlate retinal thickness with PD severity and duration.
    • Recent Swept Source OCT studies report increased choroidal thickness in PD patients.

    Conclusions:

    • OCT is a valuable tool for detecting retinal and choroidal changes in Parkinson's disease.
    • Altered retinal and choroidal parameters identified via OCT may offer clinical utility for PD management.
    • Understanding visual dysfunctions associated with these changes is crucial for patient care.