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Syndemics among individuals enrolled in the PrEP Brasil Study
Raquel B De Boni1, Iona K Machado2, Mauricio T L De Vasconcellos3
1National Institute of Infectology Evandro Chagas, Lapclin STD/AIDS, Avenida Brasil 4.365, Fiocruz, Rio de Janeiro, Brazil.
Drug and Alcohol Dependence
|February 19, 2018
Summary
Syndemics, the co-occurrence of psychosocial issues, affect 24.2% of men who have sex with men and transgender women in Brazil. Integrated HIV prevention and mental health services are crucial for this population.
Area of Science:
- Public Health
- Epidemiology
- HIV Prevention
Background:
- Concurrent psychosocial problems, known as syndemics, synergistically increase HIV infection risk.
- Syndemics pose a significant challenge for effective HIV prevention strategies.
- Understanding syndemics among key populations is crucial for targeted interventions.
Purpose of the Study:
- To evaluate the prevalence of syndemics among men who have sex with men (MSM) and transgender women (TGW).
- To identify factors associated with syndemics in this population.
- To inform HIV prevention efforts within the Brazilian pre-exposure prophylaxis (PrEP) demonstration study.
Main Methods:
- Secondary cross-sectional analysis of 421 HIV-seronegative MSM/TGW from the PrEP Brasil Study.
- Syndemics defined as the presence of two or more conditions: polysubstance use, binge drinking, positive depression screen, compulsive sexual behavior, and intimate partner violence (IPV).
Main Results:
- Syndemics prevalence was 24.2% among participants.
- High prevalence of polysubstance use (22.8%) and binge drinking (51.1%) were observed.
- Associated factors included younger age, being TGW, higher education, and multiple male sexual partners.
Conclusions:
- The high prevalence of syndemics, especially polysubstance use and binge drinking, highlights an urgent need for integrated care.
- Pre-exposure prophylaxis (PrEP) delivery presents a critical opportunity to address mental and social well-being.
- Interventions should focus on diagnosing and managing syndemic conditions alongside HIV prevention.
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