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Abnormal radial artery in Down's syndrome.

R N Lo, M P Leung, K C Lau

    Archives of Disease in Childhood
    |September 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

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    Forearm arterial patterns are frequently abnormal in Down

    Area of Science:

    • Vascular anatomy
    • Genetics
    • Developmental biology

    Background:

    • Down's syndrome is associated with various congenital anomalies.
    • Vascular development can be affected in genetic disorders.

    Purpose of the Study:

    • To investigate forearm arterial patterns in individuals with Down's syndrome.
    • To document the prevalence and types of arterial aberrations.

    Main Methods:

    • Retrospective analysis of forearm arterial patterns.
    • Clinical examination and palpation of arteries.

    Main Results:

    • 16% of patients with Down's syndrome showed forearm arterial abnormalities.
    • Enlarged anterior interosseous artery was most common (8 patients).

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  • Absence or hypoplasia of the radial artery was observed in several cases.

    • Conclusions:

    • Forearm arterial variations are common in Down's syndrome.
    • These findings highlight potential developmental disruptions in vascular patterning.
    • Further research into the genetic basis of these vascular anomalies is warranted.