Related Experiment Video

Updated: Feb 14, 2026

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)
07:01

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

918

Clinico-epidemiological Profile of Pediatric Rheumatology Disorders in Eastern India

Pratap Kumar Patra1, Manish Kumar1

  • 1Department of Pediatrics, All India Institute of Medical Sciences, Patna, Bihar, India.

Journal of Natural Science, Biology, and Medicine
|February 20, 2018
PubMed

Insights

Pediatric rheumatological disorders in India are distinct from Western populations, with Juvenile Idiopathic Arthritis (JIA) being most common. Limited access to biological agents impacts treatment, highlighting a need for further investigation.

Area of Science:

  • Pediatric Rheumatology
  • Epidemiology
  • Clinical Medicine

Background:

  • Limited data exists on pediatric rheumatological disorders in India.
  • Understanding these conditions is crucial for developing evidence-based healthcare services.

Purpose of the Study:

  • To investigate the clinical and epidemiological profile of rheumatological disorders in children in India.
  • To identify common diagnoses, treatment patterns, and challenges in managing these conditions.

Main Methods:

  • A retrospective hospital-based study was conducted.
  • Data from January 2015 to December 2016 was analyzed.
  • Included clinical, laboratory findings, and treatment responses of 60 children.

Main Results:

  • Juvenile Idiopathic Arthritis (JIA) was the most frequent diagnosis, with polyarticular JIA being the predominant subtype.
  • The mean age of onset was 9.1 years; Methotrexate was the most common disease-modifying antirheumatic drug.
  • Financial constraints prevented the use of biological agents; 10% used alternative medicine.

Conclusions:

  • The clinical and epidemiological profile of pediatric rheumatological disorders in this Indian cohort differs from Western populations.
  • The lack of access to biological agents for Juvenile Idiopathic Arthritis (JIA) management warrants further consideration.
Abstract

Keywords:
Epidemiological profilepediatricsrheumatology disorders

More Related Videos

Guidelines for Elective Pediatric Fiberoptic Intubation11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

18.6K
Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry03:37

Evaluating the Effects of Different Polishing Methods on Color Stability of Dental Restorations in Pediatric Dentistry

Published on: June 6, 2025

474

Related Concept Videos

Introduction to Epidemiology01:26

Introduction to Epidemiology

Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
1.9K
Causality in Epidemiology01:21

Causality in Epidemiology

Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
1.7K
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
1.0K
Confounding in Epidemiological Studies01:27

Confounding in Epidemiological Studies

Confounding in statistical epidemiology represents a pivotal challenge, referring to the distortion in the perceived relationship between an exposure and an outcome due to the presence of a third variable, known as a confounder. This variable is associated with both the exposure and the outcome but is not a direct link in their causal chain. Its presence can lead to erroneous interpretations of the exposure's effect, either exaggerating or underestimating the true association. This...
860
Bias in Epidemiological Studies01:29

Bias in Epidemiological Studies

Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:  
1.4K
Intrinsically Disordered Proteins02:18

Intrinsically Disordered Proteins

Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
19.6K