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Updated: Feb 14, 2026

Generating a Murine Orthotopic Metastatic Breast Cancer Model and Performing Murine Radical Mastectomy
Published on: November 29, 2018
Is Mastectomy Oncologically Safer than Breast-Conserving Treatment in Early Breast Cancer?
Fabian Riedel1, André Hennigs1, Sarah Hug1
1Department of Obstetrics and Gynecology, University of Heidelberg, Medical School, Heidelberg, Germany.
Aim:
To describe and discuss the evidence for oncological safety of different procedures in oncological breast surgery, i.e. breast-conserving treatment versus mastectomy.
Methods:
Literature review and discussion.
Results:
Oncological safety in breast cancer surgery has many dimensions. Breast-conserving treatment has been established as the standard surgical procedure for primary breast cancer and fits to the preferences of most breast cancer patients concerning oncological safety and aesthetic outcome.
Conclusions:
Breast-conserving treatment is safe. Nonetheless, the preferences of the individual patients in their consideration of breast conservation versus mastectomy should be integrated into routine treatment decisions.
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