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Updated: Feb 14, 2026
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A Mouse Model of Chronic Liver Fibrosis for the Study of Biliary Atresia
Published on: February 3, 2023
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Choanal Atresia: Birth Without Breath.
Vikas Sinha1, Samanth Talagauara Umesh2, Sushil G Jha2
11Sir T. General Hospital, Government Medical College, Bhavnagar, Bhavnagar, Gujarat India.
Summary
Hegar
Area of Science:
- Otolaryngology
- Pediatric Surgery
Background:
- Choanal atresia, a congenital condition causing nasal obstruction, presents a significant challenge in neonates.
- Bilateral choanal atresia is a medical emergency requiring prompt surgical intervention.
Purpose of the Study:
- To evaluate the efficacy and safety of using Hegar's dilators for surgical correction of choanal atresia.
- To assess surgical outcomes in patients with choanal atresia, including those with CHARGE Syndrome.
Main Methods:
- A retrospective study of 22 patients who underwent surgery for choanal atresia by the first author.
- Surgical correction involved using Hegar's dilators to address bony or membranous atresia.
- Nasal stenting was employed in all cases post-operatively.
Main Results:
- Hegar's dilators proved to be a safe and simple surgical method for choanal atresia.
- Complete nasal patency was achieved in all surgically treated cases.
- While surgery was successful, 8 neonates with CHARGE Syndrome did not survive due to their underlying condition, unrelated to surgical outcomes.
- 14 cases not associated with CHARGE Syndrome showed good postoperative recovery.
Conclusions:
- Hegar's dilators offer a safe and effective surgical approach for choanal atresia.
- Nasal stenting is crucial for preventing restenosis after surgical correction.
- While surgical outcomes for choanal atresia are generally positive, associated conditions like CHARGE Syndrome significantly impact patient survival.
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