Platelets at the Vascular Interface

Wolfgang Bergmeier1,2, Lucia Stefanini3

  • 1Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill (NC), USA.

In this brief review paper, we will summarize the State-of-the-Art on how platelet reactivity is regulated in circulation and at sites of vascular injury. Our review discusses recent and ongoing work, presented at this year's International Society on Thrombosis and Haemostasis (ISTH) meeting, on the role of platelets in (1) classical hemostasis at sites of mechanical injury, and (2) the maintenance of vascular integrity at sites of inflammation.

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