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Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
Published on: December 8, 2010
Case Report of Empagliflozin-Induced Cutaneous Polyarteritis Nodosa
Derek To1, Scott Bradshaw2, Jennifer Lipson1
11 Division of Dermatology, Department of Medicine, The Ottawa Hospital, Ottawa, ON, Canada.
Abstract:
Polyarteritis nodosa (PAN) is a rare vasculitis affecting medium-sized vessels. Cutaneous PAN is a clinical variant, and we report the first case of empagliflozin-induced cutaneous PAN in a 69-year-old man. After starting empagliflozin, the patient presented with tender subcutaneous nodules on his legs, which showed a medium-sized vessel vasculitis on histopathology. Upon cessation of this medication, he had full resolution of these nodules. This case illustrates that empagliflozin can induce cutaneous PAN, and further attention to this medication's association with cutaneous PAN is warranted.
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