Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

9.8K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
9.8K
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

285
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
285
Atomic Nuclei: Magnetic Resonance01:05

Atomic Nuclei: Magnetic Resonance

1.2K
The number of nuclear spins aligned in the lower energy state is slightly greater than those in the higher energy state. In the presence of an external magnetic field, as the spins precess at the Larmor frequency, the excess population results in a net magnetization oriented along the z axis. When a pulse or a short burst of radio waves at the Larmor frequency is applied along the x axis, the coupling of frequencies causes resonance and flips the nuclear spins of the excess population from the...
1.2K
Nuclear Magnetic Resonance (NMR): Overview01:07

Nuclear Magnetic Resonance (NMR): Overview

7.1K
Nuclear magnetic resonance (NMR) is a phenomenon exhibited by certain nuclei that can absorb characteristic radio frequency radiation under certain conditions. NMR has been extensively applied in molecular spectroscopy and medical diagnostic imaging. In both these applications, the molecule or subject under study is placed in a magnetic field and irradiated with radio frequency energy.
NMR spectroscopy generates a spectrum where the characteristic absorption frequencies of the sample are...
7.1K
Resonance02:52

Resonance

66.3K
The Lewis structure of a nitrite anion (NO2−) may actually be drawn in two different ways, distinguished by the locations of the N-O and N=O bonds.
66.3K
Optimal Foraging00:48

Optimal Foraging

14.0K
How animals obtain and eat their food is called foraging behavior. Foraging can include searching for plants and hunting for prey and depends on the species and environment.
14.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Excitation of delocalized long-lived states of aliphatic protons at low and high magnetic fields.

Magnetic resonance (Gottingen, Germany)·2026
Same author

Nature of Cr-NO Bonding from <sup>15</sup>N Solid-State NMR and X-ray Absorption Spectroscopic Signatures.

Journal of the American Chemical Society·2026
Same author

Surface Functionalities, Speciation, and Strength of Brønsted Acid Sites from a <sup>31</sup>P-<sup>109</sup>Ag NMR Tag.

Journal of the American Chemical Society·2026
Same author

Robust single-scan ultraselective NMR.

Chemical communications (Cambridge, England)·2026
Same author

Heterobimetallic Iridium-Niobia Catalyst for Efficient and Selective Methane Ammonia Reforming.

Journal of the American Chemical Society·2026
Same author

Manganese(II) and Magnesium(II) Analogies in Iridium Hydride Coordination Chemistry.

Inorganic chemistry·2026

Related Experiment Video

Updated: Feb 14, 2026

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
11:43

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging

Published on: December 30, 2016

11.1K

Tailored Microstructured Hyperpolarizing Matrices for Optimal Magnetic Resonance Imaging.

Matthieu Cavaillès1, Aurélien Bornet2, Xavier Jaurand3

  • 1Institut de Chimie de Lyon, Laboratory C2P2 UMR 5265-CNRS, Université de Lyon 1-CPE Lyon, CPE Lyon, 43 Bd du 11 Novembre 1918, 69616, Villeurbanne, France.

Angewandte Chemie (International Ed. in English)
|February 20, 2018
PubMed
Summary

Researchers developed advanced hybrid polarizing solids (HYPSO) for dynamic nuclear polarization (DNP). This breakthrough achieves high polarization levels, enabling pure hyperpolarized solutions for NMR and MRI without toxic additives.

Keywords:
dynamic nuclear polarizationhyperpolarizationmagnetic resonance imagingsilicasol-gel processes

More Related Videos

Author Spotlight: Using Hyperpolarized Xenon-129 MRI to Study Lung Diseases
09:55

Author Spotlight: Using Hyperpolarized Xenon-129 MRI to Study Lung Diseases

Published on: January 5, 2024

1.9K
Use of a Multi-compartment Dynamic Single Enzyme Phantom for Studies of Hyperpolarized Magnetic Resonance Agents
08:59

Use of a Multi-compartment Dynamic Single Enzyme Phantom for Studies of Hyperpolarized Magnetic Resonance Agents

Published on: April 15, 2016

7.2K

Related Experiment Videos

Last Updated: Feb 14, 2026

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
11:43

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging

Published on: December 30, 2016

11.1K
Author Spotlight: Using Hyperpolarized Xenon-129 MRI to Study Lung Diseases
09:55

Author Spotlight: Using Hyperpolarized Xenon-129 MRI to Study Lung Diseases

Published on: January 5, 2024

1.9K
Use of a Multi-compartment Dynamic Single Enzyme Phantom for Studies of Hyperpolarized Magnetic Resonance Agents
08:59

Use of a Multi-compartment Dynamic Single Enzyme Phantom for Studies of Hyperpolarized Magnetic Resonance Agents

Published on: April 15, 2016

7.2K

Area of Science:

  • Solid-state NMR and MRI
  • Hyperpolarization techniques
  • Materials science

Background:

  • Dynamic nuclear polarization (DNP) enhances NMR/MRI sensitivity.
  • Current DNP methods often require toxic additives or have limited performance.
  • Solid polarizing matrices offer advantages but need optimization.

Purpose of the Study:

  • To develop novel silica-based hyperpolarizing solids (HYPSO) for enhanced DNP performance.
  • To achieve high polarization levels using HYPSO materials.
  • To enable the production of pure hyperpolarized solutions for NMR/MRI.

Main Methods:

  • Tailoring physical features and porous network architecture of silica-based solids with TEMPO radicals.
  • Impregnating HYPSO materials with H2O/D2O mixtures.
  • Utilizing a 6.7 T polarizer at cryogenic temperatures (approx. 1.2 K).

Main Results:

  • Achieved unprecedented performance in dissolution DNP (d-DNP).
  • Reached high 1H polarization values up to 99%.
  • HYPSO materials combined high performance with the benefits of solid matrices.

Conclusions:

  • HYPSO materials offer a superior alternative to traditional DNP formulations.
  • Enabled hyperpolarized solutions free from toxic radicals and glass-forming agents.
  • Facilitated rapid transfer of pure hyperpolarized solutions for advanced NMR and MRI applications.