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Management of Helicobacter pylori in Piedmont, Italy
Davide G Ribaldone1, Dario Mazzucco2, Sharmila Fagoonee3
1Division of Gastroenterology, Department of Medical Sciences, University of Turin, Turin, Italy - davrib_1998@yahoo.com.
Insights
This review summarizes H. pylori research from Piedmont, Italy, highlighting its epidemiology, associated diseases, diagnostics, and treatment. Piedmont continues its historical legacy in H. pylori studies.
Area of Science:
- Microbiology
- Gastroenterology
- Epidemiology
Background:
- Helicobacter pylori (H. pylori) is a Gram-negative bacterium linked to gastritis, peptic ulcers, and gastric cancer.
- H. pylori infection is acquired in childhood and resides in the gastric lumen.
- The bacterium is also implicated in extra-gastroduodenal diseases.
Purpose of the Study:
- To systematically review all publications on H. pylori infection originating from the Piedmont region of Italy.
- To consolidate research on H. pylori epidemiology, associated pathologies, diagnostics, and treatment within this specific Italian region.
Main Methods:
- A systematic literature review was conducted using PubMed and Scopus databases.
- The search covered publications from 1965 to 2017 focusing on H. pylori management in adults in Piedmont.
- Key aspects analyzed included epidemiology, gastric and extragastric diseases, diagnostic methods, treatment, and reinfection.
Main Results:
- Piedmont has a significant body of research on H. pylori, with nearly 70 publications.
- The review covers the spectrum of H. pylori's impact, from gastric conditions to extragastric manifestations.
- Diagnostic and treatment strategies, alongside the potential for reinfection, were examined.
Conclusions:
- Piedmont upholds a strong research tradition in H. pylori studies, continuing the work of early pioneers.
- The region's publications provide a comprehensive overview of H. pylori infection management.
- This review consolidates regional contributions to understanding and managing H. pylori infection.
Abstract:
Helicobacter pylori (H. pylori) is a Gram-negative bacterium, usually acquired during childhood, whose natural habitat is the gastric lumen. H. pylori is accepted as the most important cause of gastritis and peptic ulcer in humans. Nevertheless, its important role in the pathogenesis of gastric cancer as well as in several extra-gastroduodenal diseases has been confirmed. The aim of this work is to discuss, for the first time in a single article, all publications concerning H. pylori infection arising from Piedmont region, Italy, where in 1893 Giulio Bizzozero was the first who observed and described spiral organisms in the stomach of animal models. A systematic review of all publications on the management of H. pylori in adults in Piedmont, based on a PubMed and a Scopus research from 1965 to 2017 was performed. The discussed aspects are the epidemiology, the study on gastric and extragastric diseases related to H. pylori, the diagnostic methods, the treatment of H. pylori infection, and the possibility of reinfection. In conclusions, with almost 70 publications, Piedmont has proudly maintained the tradition of the father of the H. pylori.
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