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German Value Set for the EQ-5D-5L.

Kristina Ludwig1,2, J-Matthias Graf von der Schulenburg3, Wolfgang Greiner4

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This study developed a German value set for the EQ-5D-5L (EuroQol 5 Dimensions 5 Levels) instrument, reflecting societal preferences. The new value set uses an improved protocol and enables broader use in health economic evaluations.

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Area of Science:

  • Health Economics
  • Psychometrics
  • Societal Preferences

Background:

  • The EQ-5D-5L (EuroQol 5 Dimensions 5 Levels) instrument measures health status.
  • Developing country-specific value sets is crucial for accurate health economic evaluations.
  • Previous EQ-5D-5L valuation studies lacked robust quality control and feedback mechanisms.

Purpose of the Study:

  • To develop a value set for the EQ-5D-5L instrument based on German societal preferences.
  • To implement the improved EuroQol Group valuation protocol 2.0 for the first time globally.
  • To ensure the value set's validity through internal feedback and rigorous quality control.

Main Methods:

  • A representative sample of the German population (n=1158) participated.
  • A composite time trade-off (TTO) and discrete choice experiment (DCE) were employed.
  • Econometric modeling, including conditional logit and Tobit models, estimated values for 3125 health states.

Main Results:

  • A comprehensive German EQ-5D-5L value set was generated.
  • The value set demonstrated logically consistent parameter estimates.
  • Predicted EQ-5D-5L index values ranged from -0.661 to 1.

Conclusions:

  • The study successfully created a German value set for the EQ-5D-5L, reflecting population preferences.
  • The novel application of valuation protocol 2.0 ensures enhanced data quality and validity.
  • This value set facilitates the use of EQ-5D-5L in German health economic and clinical studies.