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Updated: Feb 14, 2026

Rat Model of Adhesive Capsulitis of the Shoulder
Published on: September 28, 2018
Evaluating Nonoperative Treatments for Adhesive Capsulitis
Ryan C Xiao1, Joseph P DeAngelis1, Christopher C Smith1
1Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Adhesive capsulitis, or frozen shoulder, is often misdiagnosed. This review clarifies its presentation, pathophysiology, and nonoperative treatments for better patient care.
Area of Science:
- Orthopaedic Surgery
- Musculoskeletal Diseases
Background:
- Shoulder complaints are common in primary care and orthopaedic settings.
- Differential diagnoses include rotator cuff tears, impingement, osteoarthritis, and adhesive capsulitis (frozen shoulder).
- Adhesive capsulitis is frequently misdiagnosed, and its management is not well-defined.
Purpose of the Study:
- To review the clinical presentation of adhesive capsulitis.
- To provide an overview of the pathophysiology of adhesive capsulitis.
- To evaluate nonoperative treatment options for adhesive capsulitis.
Main Methods:
- Literature review of adhesive capsulitis.
- Analysis of diagnostic criteria and clinical presentation.
- Evaluation of existing nonoperative treatment strategies.
Main Results:
- Adhesive capsulitis presents with characteristic shoulder stiffness and pain.
- Pathophysiology involves inflammation and fibrosis of the shoulder capsule.
- Nonoperative treatments show variable efficacy, requiring individualized approaches.
Conclusions:
- Accurate diagnosis of adhesive capsulitis is crucial for effective management.
- Understanding the pathophysiology aids in developing targeted treatments.
- Further research is needed to optimize nonoperative care for frozen shoulder.
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