Recent advances on antimicrobial wound dressing: A review

Area of Science:

• Infectious Diseases
• Biomaterials Science
• Wound Healing Research

Background:

• Skin and soft tissue infections (SSTIs) present significant morbidity and mortality risks.
• Deep-seated SSTIs involving subcutaneous tissue, fascia, or muscle are challenging to treat and can become life-threatening.
• Current treatments necessitate the development of more effective therapeutic strategies.

Purpose of the Study:

• To review prominent antibacterial agents used in wound dressings.
• To discuss the mechanisms of action of these antimicrobial agents.
• To explore recent clinical advances and future perspectives in antibacterial wound dressings.

Main Methods:

• Literature review of scientific articles and clinical studies.
• Analysis of antibacterial agents incorporated into wound dressing formulations.
• Discussion of therapeutic approaches and future trends in the field.

Main Results:

• Various antimicrobial agents are being integrated into wound dressings to combat bacterial colonization.
• These agents demonstrate diverse mechanisms to reduce infection and promote healing.
• Recent clinical advancements and innovative future perspectives are emerging.

Conclusions:

• Antibacterial wound dressings represent a viable therapeutic option for managing SSTIs.
• Further research into novel agents and delivery systems is crucial for optimizing wound healing.
• The development of advanced wound dressings holds promise for reducing the burden of SSTIs.