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Updated: Feb 14, 2026

Minimal Erythema Dose MED Testing
Published on: May 28, 2013
Pediatric Lip Adhesion Following Bullous Erythema Multiforme and Review of Similar Oral Complications
Rosalind Ashton1, Karen W Wong2, Miriam Weinstein3
11 King's College London, St John's Institute of Dermatology, London, UK.
Background:
Erythema multiforme (EM) is a mucocutaneous disease most often associated with preceding herpes simplex virus or Mycoplasma pneumoniae infection. It is characterized by targetoid lesions occurring on the limbs and head and neck. Mucosal involvement can be extensive.
Objective:
We report a case of lip adhesion as a complication of EM in a child who required corrective surgery and review similar oral commissure complications.
Methods:
We completed a review of the literature for similar cases using PubMed and Medline.
Conclusions And Relevance:
We present the youngest report of lip adhesion due to striking mucositis related to EM. Sequelae of erythema multiforme can be significant, in our case requiring surgery. Meticulous oral hygiene should be encouraged when mucosal lesions are identified.
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