Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Crossing Over01:34

Crossing Over

172.3K
Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process...
172.3K
Oogenesis02:07

Oogenesis

70.1K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
70.1K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

37.3K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
37.3K
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

9.3K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
9.3K
What is Meiosis?01:36

What is Meiosis?

258.0K
Meiosis is the process by which diploid cells divide to produce haploid daughter cells. In humans, each diploid cell contains 46 chromosomes, half from the mother and half from the father. Following meiosis, the resulting haploid eggs or sperm only contain 23 chromosomes; however, each of these chromosomes contains a unique combination of parental information that results from the meiotic process of crossing over.
258.0K
Meiosis II01:57

Meiosis II

209.0K
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each...
209.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pregnancy Management and Outcomes with Hypertrophic Cardiomyopathy.

CJC open·2026
Same author

Stress and Coronary Vascular Dysfunction in Women With Prior Preeclampsia.

Hypertension (Dallas, Tex. : 1979)·2026
Same author

Hypertensive Disorders of Pregnancy and Premature Cardiovascular Disease in a Diverse Cohort of Young US Women.

Circulation·2026
Same author

Pregnancy-Related Differences in Cardiogenic Shock: A National Analysis of Etiology, Risk Factors, and Outcomes.

JACC. Advances·2025
Same author

Complement C5 inhibition in early onset HELLP syndrome.

Blood advances·2025
Same author

Association of Prepregnancy Cardiometabolic Factors With Gestational Diabetes Among Asian Populations in the United States.

JACC. Asia·2024

Related Experiment Video

Updated: Feb 14, 2026

Determining the Role of Maternally-Expressed Genes in Early Development with Maternal Crispants
10:08

Determining the Role of Maternally-Expressed Genes in Early Development with Maternal Crispants

Published on: December 21, 2021

2.6K

Maternal sepsis.

Arthur Jason Vaught1

  • 1John Hopkins School of Medicine, 600 N. Wolfe St, Phipps 228, Baltimore, MD 21287.

Seminars in Perinatology
|February 22, 2018
PubMed
Summary
This summary is machine-generated.

Sepsis significantly impacts maternal health, causing morbidity and mortality globally. This article outlines essential steps for obstetric practitioners to ensure prompt and safe patient recovery from sepsis.

Keywords:
Early goal directed therapyMaternal sepsisSeptic shock

More Related Videos

Author Spotlight: Advanced Integrated Model for Sepsis-Induced Myopathy and Single-Cell Metabolic Analysis
04:01

Author Spotlight: Advanced Integrated Model for Sepsis-Induced Myopathy and Single-Cell Metabolic Analysis

Published on: June 14, 2024

1.5K
Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies
07:34

Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies

Published on: April 11, 2012

20.1K

Related Experiment Videos

Last Updated: Feb 14, 2026

Determining the Role of Maternally-Expressed Genes in Early Development with Maternal Crispants
10:08

Determining the Role of Maternally-Expressed Genes in Early Development with Maternal Crispants

Published on: December 21, 2021

2.6K
Author Spotlight: Advanced Integrated Model for Sepsis-Induced Myopathy and Single-Cell Metabolic Analysis
04:01

Author Spotlight: Advanced Integrated Model for Sepsis-Induced Myopathy and Single-Cell Metabolic Analysis

Published on: June 14, 2024

1.5K
Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies
07:34

Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies

Published on: April 11, 2012

20.1K

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Sepsis is a critical global health issue, leading to significant maternal morbidity and mortality.
  • Prompt recognition and management are vital for improving outcomes in affected mothers.
  • Existing guidelines aim to standardize care for sepsis patients.

Purpose of the Study:

  • To provide obstetric practitioners with evidence-based, rational steps for managing sepsis in pregnant and postpartum patients.
  • To enhance the safe and expeditious recovery of mothers affected by sepsis.
  • To serve as a practical guide for clinical decision-making in obstetric sepsis cases.

Main Methods:

  • Review of current clinical guidelines and best practices for sepsis management.
  • Synthesis of evidence regarding obstetric-specific considerations in sepsis care.
  • Development of a stepwise approach for patient recovery.

Main Results:

  • Identification of key diagnostic criteria and early management strategies for obstetric sepsis.
  • Outline of critical interventions including fluid resuscitation, antibiotic therapy, and source control.
  • Emphasis on multidisciplinary team collaboration for optimal patient outcomes.

Conclusions:

  • Effective management of obstetric sepsis requires adherence to established guidelines and timely interventions.
  • A structured approach can significantly improve maternal outcomes and reduce mortality.
  • Continuous education and familiarity with sepsis protocols are crucial for obstetric practitioners.