MicroRNA Changes in Firefighters

Kyoung Sook Jeong1, Jin Zhou, Stephanie C Griffin

  • 1Department of Community, Environment and Policy, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona (Dr Jeong, Dr Griffin, Ms Dearmon-Moore, Ms Littau, Dr Burgess); Department of Occupational and Environmental Medicine, Graduate School of Medicine Dongguk University-Seoul, Dongguk University Ilsan Hospital, Goyang, Republic of Korea (Dr Jeong); Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona (Drs Zhou, Jacobs, Ms Zhai); Tucson Fire Department, Tucson, Arizona (Mr Gulotta, Mr Moore); WellAmerica, Tucson, Arizona (Dr Peate); University of Arizona Genetics Core, Arizona Research Laboratories, University of Arizona, Tucson, Arizona (Richt).

Summary

Firefighter cancer risk may be linked to altered microRNA (a type of small RNA molecule) expression. This study found differences in microRNA levels between experienced and new firefighters, suggesting potential cancer mechanisms.

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