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Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays
Published on: September 26, 2011
Previously Diagnosed HIV-Positive Persons: The Role of Centers for Disease Control and Prevention-Funded HIV Testing
Puja Seth1, Guoshen Wang, Lisa Belcher
1From the Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA.
Insights
Nearly half of HIV-positive tests are among previously diagnosed individuals. Many require re-engagement into HIV care, highlighting the need to address linkage and retention barriers for this population.
Area of Science:
- Public Health
- Infectious Disease Epidemiology
- HIV/AIDS Research
Background:
- Increased human immunodeficiency virus (HIV) testing has led to retesting of previously diagnosed individuals.
- This study evaluates Centers for Disease Control and Prevention (CDC)-funded HIV testing programs.
- Focus is on how these programs address the needs of previously diagnosed persons.
Purpose of the Study:
- To examine CDC-funded HIV testing programs.
- To assess the needs of previously diagnosed persons.
- To evaluate linkage to care for previously diagnosed HIV-positive individuals.
Main Methods:
- Analysis of demographic and test setting data for previously diagnosed HIV-positive persons in 2015.
- Examination of CDC-funded HIV testing, HIV positivity, current care status, and linkage to care.
- Assessment of trends in HIV positivity and previously diagnosed HIV-positivity from 2011 to 2015.
Main Results:
- In 2015, 48.8% of HIV-positive tests (13,528) were among previously diagnosed persons.
- Only 11.6% of previously diagnosed persons were already in HIV care.
- 62.1% of previously diagnosed persons were linked to care within 90 days (excluding those already in care).
- The proportion of previously diagnosed persons among all HIV-positive tests increased from 25.9% in 2011 to 34.1% in 2015 (P < 0.001).
Conclusions:
- A significant proportion of HIV-positive tests involve previously diagnosed individuals, with a low percentage currently in care.
- Linkage to care is crucial for previously diagnosed persons, whether they were never linked or need re-engagement.
- Barriers to linkage and retention in care for this population require focused attention and intervention.
Background:
Increased HIV testing efforts have resulted in retesting previously diagnosed persons. This study examined Centers for Disease Control and Prevention (CDC)-funded HIV testing programs to evaluate how the needs of previously diagnosed persons are being addressed.
Methods:
The following were examined by demographic and test setting among previously diagnosed HIV-positive persons in 2015: CDC-funded HIV testing, previously diagnosed HIV positivity, current care status, and linkage to care. In addition, trends of HIV positivity and previously diagnosed HIV-positivity were examined from 2011 to 2015.
Results:
In 2015, CDC funded 3,026,074 HIV tests, and 27,729 were HIV-positive tests. Of those, 13,528 (48.8%) were previously diagnosed persons. Only 11.6% of previously diagnosed persons reported already being in HIV care; after excluding them, 62.1% of previously diagnosed persons were linked within 90 days. In addition, the percentage of previously diagnosed persons steadily increased from 2011 (25.9%) to 2015 (34.1%; P < 0.001).
Conclusions:
Almost half of all HIV-positive tests were among previously diagnosed persons, but only 11.6% were already in HIV care. Linkage is necessary among persons who already know their HIV status because they either were never linked or need to be reengaged into care. Barriers in linkage and retention among this group also need to be addressed.
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