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The internal energy of a thermodynamic system is the sum of the kinetic and potential energies of all the molecules or entities in the system. The kinetic energy of an individual molecule includes contributions due to its rotation and vibration, as well as its translational energy. The potential energy is associated only with the interactions between one molecule and the other molecules of the system. Neither the system's location nor its motion is of any consequence as far as the internal...
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Related Experiment Video

Updated: Feb 14, 2026

Microsurgical Skills of Establishing Permanent Jugular Vein Cannulation in Rats for Serial Blood Sampling of Orally Administered Drug
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Simulated internal jugular vein cannulation using a needle-guiding device.

Ji Hoon Kim1, Jin Ha Park2, Junho Cho1

  • 1Department of Emergency Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.

The American Journal of Emergency Medicine
|February 23, 2018
PubMed
Summary
This summary is machine-generated.

A new disposable device significantly improved first-attempt success rates for ultrasound-guided internal jugular vein cannulation in a simulation study. This innovation reduced procedure attempts and complications, enhancing user comfort.

Keywords:
CannulationDeviceInternal jugular veinUltrasound

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Area of Science:

  • Medical Simulation
  • Vascular Access Procedures
  • Medical Device Innovation

Background:

  • Internal jugular vein cannulation is crucial for central venous access.
  • The two-dimensional ultrasound-guided approach does not guarantee first-attempt success.
  • Improving first-attempt success rates is essential to minimize patient risk and procedural burden.

Purpose of the Study:

  • To evaluate a novel disposable device's efficacy in improving first-attempt success rates for ultrasound-guided internal jugular vein cannulation.
  • To assess the device's impact on mechanical complications, procedure time, and perceived difficulty.

Main Methods:

  • A randomized, parallel simulation study involving 88 participants.
  • Participants performed simulated internal jugular vein cannulation using ultrasound guidance, with or without the new device.
  • Primary outcome: success rate of the first cannulation attempt. Secondary outcomes: mechanical complications, procedure time, difficulty level.

Main Results:

  • The device group achieved a 75.0% first-attempt success rate compared to 27.3% in the control group (P<0.001).
  • Significantly fewer attempts were needed with the device (1.63 vs. 5.59, P<0.001).
  • Participants reported greater comfort using the device during the procedure (P<0.0001).

Conclusions:

  • The new disposable device is effective in increasing first-attempt success for ultrasound-guided internal jugular vein cannulation.
  • The device shows potential for reducing complications and procedure time.
  • Further clinical trials are warranted to confirm these findings in patient populations.