Atypical Location of Intracerebral Hemorrhage in Moyamoya Disease
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Updated: Feb 14, 2026

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
Published on: October 15, 2021
Zainah A Abuoliat1, Basma A AlFarhan1, Aysha A Alshahrani1
1College of Medicine, King Saud Bin Abdulaziz University for Health Sciences.
Abstract:
Moyamoya disease is a chronic, progressive bilateral occlusion or stenosis of terminal internal carotid arteries as well as the proximal anterior and middle cerebral arteries. Hemorrhage of the splenium of the corpus callosum rarely occurs with moyamoya disease. In this article, we report a case of a 53-year-old woman diagnosed with moyamoya disease by cerebral angiography. She presented to the emergency department complaining of unsteadiness and a tendency to fall forward for one week. The patient was investigated with head computed tomography (CT) scan upon presentation revealing atypical location of hemorrhage in the corpus callosum, mainly in the splenium.
Insights
Moyamoya disease, a rare condition causing blocked arteries, can lead to unusual brain hemorrhages. This case highlights a rare splenium of the corpus callosum hemorrhage in a moyamoya patient.
Area of Science:
- Neurology
- Vascular Neurology
- Neuroimaging
Background:
- Moyamoya disease is a rare, progressive cerebrovascular disorder characterized by stenosis or occlusion of the terminal internal carotid arteries and proximal anterior and middle cerebral arteries.
- Hemorrhage, particularly in atypical locations, is an uncommon but serious complication of moyamoya disease.
Observation:
- A 53-year-old woman presented with a one-week history of unsteadiness and a tendency to fall forward.
- Cerebral angiography confirmed the diagnosis of moyamoya disease.
- Head computed tomography (CT) scan revealed an atypical hemorrhage in the splenium of the corpus callosum.
Findings:
- The patient's symptoms were attributed to a rare manifestation of moyamoya disease: hemorrhage in the splenium of the corpus callosum.
- The imaging findings underscore the diverse clinical presentations of moyamoya disease.
Implications:
- This case expands the understanding of potential hemorrhagic complications in moyamoya disease.
- Highlights the importance of considering moyamoya disease in patients presenting with neurological symptoms and atypical intracranial hemorrhages.
- Emphasizes the role of advanced neuroimaging in diagnosing rare cerebrovascular conditions and their complications.
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