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Updated: Feb 14, 2026

Orthotopic Mouse Model of Colorectal Cancer
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In vitro and in vivo Limiting Dilution Assay for Colorectal Cancer

L Agro1,2, C O'Brien1,2,3,4

  • 1Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.

Bio-Protocol
|February 23, 2018
PubMed
Summary

Limiting dilution assays (LDAs) measure colorectal cancer initiating cell (CC-IC) frequency. These assays evaluate treatment effects on CC-IC frequency in vitro and in vivo.

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