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Acute-onset endophthalmitis caused by Staphylococcus lugdunensis

Robert B Garoon1, Darlene Miller1, Harry W Flynn1

  • 1Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL, USA.

American Journal of Ophthalmology Case Reports
|February 23, 2018
PubMed
Abstract

Insights

Staphylococcus lugdunensis can cause acute-onset endophthalmitis, with outcomes varying by patient. Vancomycin effectively treats this infection, offering consistent coverage for bacterial endophthalmitis.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Acute-onset endophthalmitis is a severe intraocular infection.
  • Staphylococcus lugdunensis is an emerging pathogen in endophthalmitis.
  • Understanding its clinical presentation and antimicrobial susceptibility is crucial.

Observation:

  • A case series of six patients with acute-onset endophthalmitis due to Staphylococcus lugdunensis.
  • Etiologies included post-cataract surgery, open globe injury, and intravitreal injection.
  • Visual acuity outcomes were variable, with 50% achieving ≥20/40.

Findings:

  • Staphylococcus lugdunensis isolates were uniformly sensitive to vancomycin.
  • Resistance to oxacillin and ciprofloxacin was observed in some isolates.
  • Vancomycin demonstrated consistent efficacy against S. lugdunensis endophthalmitis.

Implications:

  • Staphylococcus lugdunensis is a significant cause of acute-onset endophthalmitis.
  • Vancomycin is a reliable treatment option for S. lugdunensis endophthalmitis.
  • Further research into S. lugdunensis pathogenicity and resistance patterns is warranted.
Keywords:
EndophthalmitisLugdunensisStaphylococcus

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