Related Experiment Video
Updated: Feb 14, 2026

06:12
Monitoring Actin Disassembly with Time-lapse Microscopy
Published on: November 8, 2006
9.0K
Correction to: Plant actin depolymerizing factor: actin microfilament disassembly and more.
1The Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma-shi, Nara, 630-0192, Japan. norikoi@bs.naist.jp.
Journal of Plant Research
|February 23, 2018
Summary
This study explores plant actin depolymerizing factor (ADF) and its role in actin microfilament disassembly. The research highlights how ADF proteins influence cytoskeletal dynamics in plants.
Area of Science:
- Plant Biology
- Cell Biology
- Biochemistry
Context:
- Actin microfilaments are crucial for plant cell structure and function.
- Actin depolymerizing factors (ADFs) are known regulators of actin dynamics.
- Understanding ADFs is key to deciphering plant cytoskeletal organization.
Purpose:
- To detail the function of plant actin depolymerizing factor (ADF).
- To elucidate the mechanisms of actin microfilament disassembly mediated by ADF.
- To explore the broader roles of ADF beyond simple depolymerization.
Summary:
- Plant actin depolymerizing factor (ADF) plays a critical role in the disassembly of actin microfilaments.
- ADF proteins interact with actin to regulate filament dynamics, influencing cell shape and motility.
- The research provides insights into the multifaceted functions of ADF in plant cellular processes.
Impact:
- Enhanced understanding of plant cytoskeletal regulation.
- Potential applications in plant biotechnology and crop improvement.
- Opens avenues for further research into ADF-mediated cellular processes.
Related Concept Videos
Actin Filament Depolymerization
4.0K
Actin filaments (F-actin) are composed of actin subunits. The dissociation of actin monomers can occur from either end of F-actin. The rate of dissociation is faster from the minus-end or the pointed end, where the actin subunits exist with a bound ADP, together known as ADP-actin. The depolymerization of F-actin is aided by proteins, including the actin-depolymerizing factor (ADF) and cofilin family of proteins, gelsolin, and glia maturation factor (GMF).
In F-actin, the ADF/cofilin proteins...
In F-actin, the ADF/cofilin proteins...
4.0K
Actin Treadmilling
9.8K
Actin filaments undergo polymerization and depolymerization from either end. The polymerization and depolymerization rates depend on the cytosolic concentration of free G-actins. The polymerization rate is generally higher at the plus or barbed end, while the depolymerization rate is higher at the minus or pointed end. At a steady state, critical concentration describes the concentration of free G-actin monomers at which the polymerization rate at the plus end is equal to that of the...
9.8K
Introduction to Actin
6.7K
Actin is a highly conserved cytoskeletal protein found abundantly in eukaryotic cells. It constitutes 10% weight of the total cellular protein in muscle cells, while in non-muscle cells, it is lower and makes up around 1–5 percent of the total cell protein. Actin found in the unicellular amoebae and complex multicellular animals is around 80% similar, demonstrating their conservation over a billion years of evolution. Actin coding genes are conserved within species and across...
6.7K
Actin Polymerization
8.6K
Actin polymerization occurs through the head-to-tail association of binding sites on monomeric actin or G-actin to form filamentous or F-actin. The polymerization can be divided into three phases ̶ nucleation, elongation, and steady-state phase.
The nucleation phase involves forming a stable nucleus consisting of three actin monomers to form a new actin filament. Actin-binding proteins such as formins and Arp2/3 complex help filament growth post-nucleation. The Formins form straight...
The nucleation phase involves forming a stable nucleus consisting of three actin monomers to form a new actin filament. Actin-binding proteins such as formins and Arp2/3 complex help filament growth post-nucleation. The Formins form straight...
8.6K
Power Factor Correction
559
The power transmission to a factory involves the transfer of apparent power, a combination of active and reactive power. The power factor measures how effectively electrical power is converted into useful work output. The ratio of the real power (KW) that does the work to the apparent power (KVA) supplied to the circuit.
559
Formation of Higher-order Actin Filaments
3.7K
The polymerization of G-actin monomers into filamentous F-actin is a multi-step process. Once the F-actins are formed, they can bundle together in different arrangements to form higher-order networks and regulate cellular functions. Common examples include the formation of lamellipodia and filopodia at the cell's leading edge by actin reorganization in a migrating cell. The microvilli on the brush border epithelial cells are also formed through the F-actin network.
The high-order actin...
The high-order actin...
3.7K

