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Author Spotlight: Implications of Non-Nutritive Sucking on Speech Emergence and Infant Development
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Nutritional influences on brain development.

Michael K Georgieff1, Sara E Ramel1, Sarah E Cusick1

  • 1Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.

Acta Paediatrica (Oslo, Norway : 1992)
|February 23, 2018
PubMed
Summary
This summary is machine-generated.

Early nutrition significantly impacts lifelong neurodevelopment. Optimizing nutrient intake during fetal and neonatal stages is crucial for long-term brain health and development.

Keywords:
BrainDevelopmentFoetusNeonateNutrition

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Area of Science:

  • Neuroscience
  • Developmental Biology
  • Nutritional Science

Background:

  • Emerging evidence highlights the critical role of nutrition during the late fetal and early neonatal periods.
  • Nutritional deficits in early life pose significant long-term risks to neurodevelopment.
  • Understanding nutrient-specific effects and sensitive developmental windows is key.

Purpose of the Study:

  • To investigate the impact of early-life nutrition on neurodevelopment across the lifespan.
  • To elucidate the mechanisms by which nutrients influence early brain growth.
  • To identify sensitive periods for nutrient provision and assess nutritional status for predicting development.

Main Methods:

  • Review of preclinical and human studies.
  • Analysis of nutrient-specific effects on neurodevelopment.
  • Exploration of mechanisms influencing early brain development.

Main Results:

  • Specific nutrients have a profound impact during the late fetal and early neonatal periods.
  • Nutritional deficits during these critical windows increase long-term neurodevelopmental risks.
  • Mechanisms and sensitive periods for nutrient intervention are being actively researched.

Conclusions:

  • Optimizing nutrition during fetal and early postnatal life presents a critical opportunity.
  • Early nutritional interventions can significantly impact neurodevelopment and lifelong brain function.
  • Nutritional status assessment is vital for evaluating early-life nutritional therapies.