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Cost-effectiveness thresholds: methods for setting and examples from around the world.

André Soares Santos1, Augusto Afonso Guerra-Junior1,2, Brian Godman3,4

  • 1a Department of Social Pharmacy, College of Pharmacy , Universidade Federal de Minas Gerais (UFMG) , Belo Horizonte , Brazil.

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|February 23, 2018
PubMed
Summary
This summary is machine-generated.

Cost-effectiveness thresholds (CETs) are crucial for healthcare value assessment. Defining these thresholds is essential for transparent and efficient Health Technology Assessment (HTA) systems globally.

Keywords:
Cost-benefit analysiscost-effectiveness analysiseconomics, medicaleconomics, pharmaceuticalexpert testimonyreviewtechnology assessment, biomedical

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Area of Science:

  • Health Economics
  • Health Technology Assessment (HTA)

Background:

  • Cost-effectiveness thresholds (CETs) are vital for evaluating healthcare interventions' value for money.
  • The study addresses the need for defining CETs in the Brazilian HTA context.

Purpose of the Study:

  • To explore methods for calculating cost-effectiveness thresholds.
  • To highlight the importance of CETs in healthcare prioritization.

Main Methods:

  • Systematic literature search across major databases (PubMed, Lilacs, ScienceDirect).
  • Complementary searches including Google Scholar and conference abstracts.
  • Review of established approaches for CET calculation: willingness-to-pay, precedent, and opportunity cost methods.

Main Results:

  • CETs serve as a bridge between academic research and healthcare decision-making.
  • Three primary methods exist for calculating CETs, though explicit thresholds are rarely formally adopted.
  • Implicit thresholds can be inferred from funded healthcare cases.

Conclusions:

  • Establishing a clear cost-effectiveness threshold is fundamental for transparent and efficient Health Technology Assessment.
  • The definition of CETs is paramount for effective healthcare prioritization.