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Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
Published on: July 5, 2017
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Recent Advances in Development of Polyphenols as Anticancer Agents
Sreekanth Thota1,2, Daniel Alencar Rodrigues2, Eliezer J Barreiro2
1National Institute for Science and Technology on Innovation on Neglected Diseases (INCT/IDN), Center for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Av. Brazil 4036, Manguinhos, 21040-361 - Rio de Janeiro - RJ, Brazil.
Mini Reviews in Medicinal Chemistry
|February 23, 2018
Summary
Polyphenols, natural compounds found in plants, show promise as novel antitumor agents. Further research into these diverse molecules is essential for developing new cancer therapies.
Area of Science:
- Phytochemistry
- Pharmacology
- Oncology
Background:
- Curative therapies for disseminated cancers remain limited.
- Novel chemotherapeutic agents are crucial for cancer treatment.
- Polyphenols, abundant plant-derived compounds, possess diverse structures and physiological roles.
Purpose of the Study:
- To review recent research on the development of polyphenols as antitumor agents.
- To highlight the potential of natural compounds in cancer therapy.
Main Methods:
- Literature review of scientific studies.
- Analysis of research on polyphenol structures and antitumor activities.
Main Results:
- Polyphenols exhibit a wide range of physiological activities.
- Recent studies demonstrate the antitumor potential of various polyphenols.
- Structural diversity of polyphenols contributes to their therapeutic possibilities.
Conclusions:
- Polyphenols represent a promising class of natural compounds for cancer treatment.
- Continued investigation into polyphenols could lead to new chemotherapeutic strategies.
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